De novo autoimmune hepatitis after liver transplantation Giorgina Mieli-Vergani, Diego Vergani  Journal of Hepatology  Volume 40, Issue 1, Pages 3-7 (January 2004) DOI: 10.1016/j.jhep.2003.10.022

Fig. 1 De novo autoimmune hepatitis post liver transplant. (A) Chronic hepatitis with moderate portal and interface mononuclear cell infiltrate, including plasma cells (haematoxilyn-eosin staining); (B) reticulin staining showing bridging collapse, a lesion resulting from extensive death of hepatocytes and consequent coalescence of the supportive structure (histological pictures kindly provided by Professor Bernard Portmann). Journal of Hepatology 2004 40, 3-7DOI: (10.1016/j.jhep.2003.10.022)

Fig. 2 (A) Heart transplant from an allogeneic mouse results not only in rejection, but also in the production of antibodies and CD4 T cells directed against cardiac myosin in the recipient. (B) Transplant of allogeneic skin or of a syngeneic heart do not lead to cardiac-specific autoimmunity, indicating that this response is tissue-specific and that an allogeneic response is necessary to break tolerance to cardiac myosin. Journal of Hepatology 2004 40, 3-7DOI: (10.1016/j.jhep.2003.10.022)