Volume kinetics of glucose 2

Slides:

Advertisements

Similar presentations

S. Arenas-Lopez, H. Mulla, S. Manna, A. Durward, I. A. Murdoch, S. M

Advertisements

Preventing surgical deaths: critical care and intensive care outreach services in the postoperative period D.R. Goldhill British Journal of Anaesthesia

Effects of intraoperative and early postoperative normal saline or Plasma-Lyte 148® on hyperkalaemia in deceased donor renal transplantation: a double-blind.

M. Kokki, P. Välitalo, M. Kuusisto, V. P. Ranta, K. Raatikainen, H

Validation of volume kinetic analysis of glucose 2

Functional walking capacity as an outcome measure of laparoscopic prostatectomy: the effect of lidocaine infusion S. Lauwick, D.J. Kim, G. Mistraletti,

C.-A. Ewaldsson, R.G. Hahn British Journal of Anaesthesia

M. M. Sahinovic, D. J. Eleveld, T Miyabe-Nishiwaki, M. M. R. F

Developmental pharmacokinetics of morphine and its metabolites in neonates, infants and young children N.J. Bouwmeester, B.J. Anderson, D Tibboel, N.H.G.

High concentrations of N-BNP are related to non-infectious severe SIRS associated with cardiovascular dysfunction occurring after off-pump coronary artery.

The two-compartment recirculatory pharmacokinetic model'an introduction to recirculatory pharmacokinetic concepts Upton R.N. British Journal of Anaesthesia

Prediction of tracheostomy tube size for paediatric long-term ventilation: an audit of children with spinal cord injury Behl S. , Watt J.W.H. British.

Changes in the effect of propofol in response to altered plasma protein binding during normothermic cardiopulmonary bypass E Takizawa, H Hiraoka, D Takizawa,

Pharmacokinetics of ropivacaine in patients with chronic renal failure

Changes in glomerular filtration rate after cardiac surgery with cardiopulmonary bypass in patients with mild preoperative renal dysfunction B.G. Loef,

J.-Y. Hwang, H.-S. Na, Y.-T. Jeon, Y.-J. Ro, C.-S. Kim, S.-H. Do

Prediction of volatile anaesthetic solubility in blood and priming fluids for extracorporeal circulation R.-G. Yu, J.-X. Zhou, J Liu British Journal.

Comparison of oxygen uptake during arm or leg cardiopulmonary exercise testing in vascular surgery patients and control subjects L. Loughney, M. West,

Remifentanil–midazolam sedation for paediatric patients receiving mechanical ventilation after cardiac surgery† A.E. Rigby-Jones, M.J. Priston, J.R.

Comparison of the respiratory effects of intravenous buprenorphine and fentanyl in humans and rats A Dahan, A Yassen, H Bijl, R Romberg, E Sarton, L.

T. Iirola, H. Ihmsen, R. Laitio, E. Kentala, R. Aantaa, J. -P

Intraoperative thoracic epidural anaesthesia attenuates stress-induced immunosuppression in patients undergoing major abdominal surgery† O. Ahlers, I.

Blood glucose concentration profile after 10 mg dexamethasone in non-diabetic and type 2 diabetic patients undergoing abdominal surgery Hans P , Vanthuyne.

A. Absalom, D. Amutike, A. Lal, M. White, G.N.C. Kenny

Spectral entropy measurement of patient responsiveness during propofol and remifentanil. A comparison with the bispectral index† Vanluchene A.L.G. ,

W. Ruppen, L. A. Steiner, J. Drewe, L. Hauenstein, S. Brugger, M. D

Premedication with controlled-release oxycodone does not improve management of postoperative pain after day-case gynaecological laparoscopic surgery

Nitrous oxide for monitoring fluid absorption in volunteers†

Effects of magnesium sulphate on intraoperative anaesthetic requirements and postoperative analgesia in gynaecology patients receiving total intravenous.

Fluid absorption in endoscopic surgery

Does bispectral analysis add anything but complexity

Changes in serum albumin concentration and volume expanding effects following a bolus of albumin 20% in septic patients Margarson M.P. , Soni N.C.

Comparative study of topical anaesthesia with lidocaine 2% vs levobupivacaine 0.75% in cataract surgery S.A. Fernández, E. Dios, J.C. Diz British Journal.

Postoperative intravenous morphine titration

H. Beloeil, J.-X. Mazoit, D. Benhamou, J. Duranteau

Prevalence of postoperative bladder distension and urinary retention detected by ultrasound measurement Lamonerie L , Marret E , Deleuze A , Lembert.

Predictive performance of ‘Servin's formula’ during BIS®-guided propofol-remifentanil target-controlled infusion in morbidly obese patients A. Albertin,

Pharmacokinetics of remifentanil and its major metabolite, remifentanil acid, in ICU patients with renal impairment† Pitsiu M , Wilmer A , Bodenham A.

Accuracy of feedback-controlled oxygen delivery into a closed anaesthesia circuit for measurement of oxygen consumption† A.W. Schindler, T.W.L. Scheeren,

Predictive performance of the modified Marsh and Schnider models for propofol in underweight patients undergoing general anaesthesia using target-controlled.

Volume kinetics of glucose solutions given by intravenous infusion†

Predictive performance of the Domino, Hijazi, and Clements models during low-dose target-controlled ketamine infusions in healthy volunteers A.R. Absalom,

Interstitial muscle concentrations of rocuronium under steady-state conditions in anaesthetized dogs: actual versus predicted values Ezzine S. , Varin.

II. Should anaesthetists stop infusing isotonic saline?

Pharmacokinetics of intravenous dexmedetomidine in children under 11 yr of age S. Vilo, P. Rautiainen, K. Kaisti, R. Aantaa, M. Scheinin, T. Manner, K.T.

Effects of different remifentanil target concentrations on MAC BAR of sevoflurane in gynaecological patients with CO2 pneumoperitoneum stimulus Z.-Y.

J.J. Vos, T.W.L. Scheeren, S.A. Loer, A. Hoeft, J.K.G. Wietasch

Kennedy J.M. , van Rij A.M. British Journal of Anaesthesia

Urinary, biliary and faecal excretion of rocuronium in humans

L Witt, W. A. Osthaus, T Lücke, B Jüttner, N Teich, S Jänisch, A. S

T.G. Hansen, K.F. Ilett, S.I. Lim, C. Reid, L.P. Hackett, R. Bergesio

Validity of the 6 min walk test in prediction of the anaerobic threshold before major non- cardiac surgery R.C.F. Sinclair, A.M. Batterham, S. Davies,

Assessment of pulse transit time to indicate cardiovascular changes during obstetric spinal anaesthesia† G Sharwood-Smith, J Bruce, G Drummond British.

High-fidelity patient simulation: validation of performance checklists

Rocuronium plasma concentrations during three phases of liver transplantation: relationship with early postoperative graft liver function†‡ L. Gao, I.

Small dose of clonidine mixed with low-dose ropivacaine and fentanyl for epidural analgesia after total knee arthroplasty† Förster J.G. , Rosenberg P.H.

T. Tatara, T. Tsunetoh, C. Tashiro British Journal of Anaesthesia

Effect of age on the clinical profile and systemic absorption and disposition of levobupivacaine after epidural administration Simon M.J.G. , Veering.

I.V. ropivacaine compared with lidocaine for the treatment of tinnitus

M.A. Tooley, C.L. Stapleton, G.L. Greenslade, C Prys-Roberts

Assessment of preoperative fluid depletion using bioimpedance analysis

Hypothermic responses to infection are inhibited by α2-adrenoceptor agonists with possible clinical implications S. Tolchard, P.A. Burns, D.J. Nutt,

Analgesia for day-case surgery†

The suppression of spinal F-waves by propofol does not predict immobility to painful stimuli in humans† J.H. Baars, S Tas, K.F. Herold, D.A. Hadzidiakos,

Wee L. , Barron J. , Toye R. British Journal of Anaesthesia

Plasma lidocaine concentrations following insertion of 2% lidocaine gel into the uterine cavity after uterine balloon thermal ablation G.F. Rousseau,

Volume kinetics of glucose 2

Estimation of lean body mass in children

High plasma ropivacaine concentrations after fascia iliaca compartment block in children Paut O , Schreiber E , Lacroix F , Meyrieux V , Simon N , Lavrut.

Analysis of pharmacodynamic interaction of sevoflurane and propofol on bispectral index during general anaesthesia using a response surface model J.C.

Presentation transcript:

Volume kinetics of glucose 2 Volume kinetics of glucose 2.5% solution and insulin resistance after abdominal hysterectomy Strandberg P. , Hahn R.G. British Journal of Anaesthesia Volume 94, Issue 1, Pages 30-38 (January 2005) DOI: 10.1093/bja/aeh285 Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

Fig 1 The plasma glucose concentration (a), plasma dilution (b), and the plasma insulin concentration (c) during and after the infusion of about 900 ml of glucose 2.5% with electrolytes over 45 min 2 days after abdominal hysterectomy. In a and b, the thin lines are individual curves while thick lines represent simulations based on the averaged best estimates of the kinetic parameters. c shows the mean and the error bars represent sd. British Journal of Anaesthesia 2005 94, 30-38DOI: (10.1093/bja/aeh285) Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

Fig 2 Relative changes in the hydration of the ECF and ICF from before hysterectomy and until the beginning of the third postoperative day as measured by bioimpedance. Each new day begins at 08:00. British Journal of Anaesthesia 2005 94, 30-38DOI: (10.1093/bja/aeh285) Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

Fig 3 Intercorrelations between the M value obtained during glucose clamping (subplots a and b), the protein catabolism as indicated by the urinary excretion of 3-MH (a, c, and d), and the change in ICF volume as measured by bioimpedance on the second (b) and third (d) postoperative mornings. Also shown is the ratio of glucose clearance to plasma insulin at the end of the infusion, which was subjected to kinetic analysis (c). Each point represents one patient. One outlier (open circle) was excluded from the linear regression analysis as the collection of urine was probably incomplete. British Journal of Anaesthesia 2005 94, 30-38DOI: (10.1093/bja/aeh285) Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

Fig 4 Nomogram showing the relationship between infusion rate and the infusion time required to increase the plasma glucose concentration (left) and the infusion rate required thereafter to maintain a steady-state glucose concentration (right) during the postoperative follow-up after hysterectomy (body weight 70 kg). The computer simulations for the graph were performed using the kinetic parameters from Table 2. British Journal of Anaesthesia 2005 94, 30-38DOI: (10.1093/bja/aeh285) Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

Fig 5 Nomogram showing the relationship between infusion rate and the infusion time required to dilute the plasma to a predetermined degree (left) and the infusion rate required thereafter to maintain a steady-state dilution (right) during the postoperative follow-up after hysterectomy (body weight 70 kg). The steady-state rate is given for a 30-min infusion but should be increased by 5% for the shortest infusion rate (10 min) and reduced by 5% for the longest one (60 min). British Journal of Anaesthesia 2005 94, 30-38DOI: (10.1093/bja/aeh285) Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

Fig 6 Computer simulations of the plasma glucose concentration (a), plasma dilution (b), and the volume expansion of the central (c) and peripheral (d) body fluid spaces during and after infusion of 12.5 ml kg−1 of 2.5% glucose solution in the postoperative period, during laparoscopy and in the laboratory setting. Parameter estimates from the present and two previous studies4 5 were used. British Journal of Anaesthesia 2005 94, 30-38DOI: (10.1093/bja/aeh285) Copyright © 2005 British Journal of Anaesthesia Terms and Conditions