A simple prediction score for estimating the risk of candidaemia caused by fluconazole non-susceptible strains  G. Cuervo, M. Puig-Asensio, C. Garcia-Vidal,

Slides:



Advertisements
Similar presentations
Models for the organisation of hospital infection control and prevention programmes B. Gordts Clinical Microbiology and Infection Volume 11, Pages
Advertisements

Candida species distribution and antifungal susceptibility testing according to European Committee on Antimicrobial Susceptibility Testing and new vs.
Analysis of clinical and environmental Candida parapsilosis isolates by microsatellite genotyping—a tool for hospital infection surveillance  R. Sabino,
L. Boyanova  Clinical Microbiology and Infection 
Clinical Microbiology and Infection
KLIC-score for predicting early failure in prosthetic joint infections treated with debridement, implant retention and antibiotics  E. Tornero, L. Morata,
I.J. Schalk  Clinical Microbiology and Infection 
A simple prediction score for estimating the risk of candidaemia caused by fluconazole non-susceptible strains  G. Cuervo, M. Puig-Asensio, C. Garcia-Vidal,
Distribution of fluconazole-resistant Candida bloodstream isolates among hospitals and inpatient services in Israel  R. Ben-Ami, G. Rahav, H. Elinav,
O.J. Dyar, G. Tebano, C. Pulcini  Clinical Microbiology and Infection 
D. Khalil, M. Hultin, M.U. Rashid, B. Lund 
P. Clarke, S. Murchan, E.G. Smyth, H. Humphreys 
Control of multidrug-resistant Gram-negative bacteria in low- and middle-income countries—high impact interventions without much resources  N. Singh,
Differential association of fluconazole dose and dose/MIC ratio with mortality in patients with Candida albicans and non-albicans bloodstream infection 
In vitro activity of several antimicrobial peptides against colistin-susceptible and colistin- resistant Acinetobacter baumannii  X. Vila-Farres, C. Garcia.
Risk factors for cryptococcal infection among patients with rheumatoid arthritis receiving different immunosuppressive medications  T.-L. Liao, Y.-M.
Migrant health—a cause for concern?
Candida glabrata fungaemia in intensive care units
Discontinuation of echinocandin and azole treatments led to the disappearance of an FKS alteration but not azole resistance during clonal Candida glabrata.
Quinolone resistance among Shigella spp
A. F. Simonetti, C. Garcia-Vidal, D. Viasus, D. García-Somoza, J
Clinical impact and prevalence of MRSA CC398 and differences between MRSA-TetR and MRSA-TetS in an area of Spain with a high density of pig farming: a.
Distribution of fluconazole-resistant Candida bloodstream isolates among hospitals and inpatient services in Israel  R. Ben-Ami, G. Rahav, H. Elinav,
Extended-spectrum β-lactamase/AmpC- and carbapenemase-producing Enterobacteriaceae in animals: a threat for humans?  J.-Y. Madec, M. Haenni, P. Nordmann,
How to evaluate and predict the ecologic impact of antibiotics: the pharmaceutical industry view from research and development  R. Bax  Clinical Microbiology.
Dermatitis by Dermatophilus congolensis
Antimicrobial susceptibility of Streptococcus pneumoniae in Latin America: results from five years of the SENTRY Antimicrobial Surveillance Program  M.
Epidemiology, risk factors and impact on long-term pancreatic function of infection following pancreas-kidney transplantation  J.M. Herrero-Martínez,
Should standardized susceptibility testing for microbial biofilms be introduced in clinical practice?  T. Coenye, D. Goeres, F. Van Bambeke, T. Bjarnsholt 
Potential risk factors for infection with Candida spp
Clinical Microbiology and Infection
W. Witte, B. Pasemann, C. Cuny  Clinical Microbiology and Infection 
Epidemiology of invasive fungal infections due to Aspergillus spp
H. Adibhesami, M. Douraghi, M. Rahbar, A. Abdollahi 
Identification of genetic markers of resistance to echinocandins, azoles and 5- fluorocytosine in Candida glabrata by next-generation sequencing: a feasibility.
Assessment of nephrotoxicity in patients receiving amphotericin B lipid complex: a pharmacosurveillance study in Spain  J.-M. Aguado, C. Lumbreras, D.
Early initiation of appropriate treatment is associated with increased survival in cancer patients with Candida glabrata fungaemia: a potential benefit.
Vector control: a cornerstone in the malaria elimination campaign
C. Garcia-Vidal, I. Sanchez-Rodriguez, A. F. Simonetti, J. Burgos, D
Switch to oral antibiotics in the treatment of infective endocarditis is not associated with increased risk of mortality in non–severely ill patients 
A. Solé, P. Morant, M. Salavert, J. Pemán, P. Morales 
Candida species distribution and antifungal susceptibility testing according to European Committee on Antimicrobial Susceptibility Testing and new vs.
Identification of patients at high risk for Clostridium difficile infection: development and validation of a risk prediction model in hospitalized patients.
Isospora belli Clinical Microbiology and Infection
Unveiling the molecular basis of antimicrobial resistance in Staphylococcus aureus from the Democratic Republic of the Congo using whole genome sequencing 
S. Bengtsson, C. Bjelkenbrant, G. Kahlmeter 
Antimicrobial susceptibility in Escherichia coli of human and avian origin—a comparison of wild-type distributions  M. Sjölund, S. Bengtsson, J. Bonnedahl,
Metagenomics and probiotics
Previously unknown species of Aspergillus
Systematic review of antibiotic consumption in acute care hospitals
Update on antifungal resistance in Aspergillus and Candida
Harmonised monitoring of antimicrobial resistance in Salmonella and Campylobacter isolates from food animals in the European Union  S. Bronzwaer  Clinical.
Eleven-year retrospective survey of candidaemia in a university hospital in southwestern Greece  A. Spiliopoulou, S. Vamvakopoulou, C. Bartzavali, G.
M. Daudin, P. Tattevin, B. Lelong, E. Flecher, S. Lavoué, C. Piau, A
Twelve years of fluconazole in clinical practice: global trends in species distribution and fluconazole susceptibility of bloodstream isolates of Candida 
Circulation of international clones of levofloxacin non-susceptible Streptococcus pneumoniae in Taiwan  Y.-C. Hsieh, L.-Y. Chang, Y.-C. Huang, H.-C. Lin,
An after-hours clinical liaison blood culture service—is it worth it?
Increasing numbers of hospitalizations and deaths with mention of Clostridium difficile infection, north-eastern Italy, 2008–2013  U. Fedeli, E. Schievano,
Changing pattern of candidaemia 2001–2006 and use of antifungal therapy at the University Hospital of Vienna, Austria  E. Presterl, F. Daxböck, W. Graninger,
Initial use of combination treatment does not impact survival of 106 patients with haematologic malignancies and mucormycosis: a propensity score analysis 
E. Tacconelli  Clinical Microbiology and Infection 
Abstracts Clinical Microbiology and Infection
Virology: a scientific discipline facing new challenges
Modification of prescribers’ behavior: the Icelandic approach
In vitro activity of a new echinocandin, LY303366, and comparison with fluconazole, flucytosine and amphotericin B against Candida species†   C.B. Moore,
J.L. Balcázar  Clinical Microbiology and Infection 
Epidemiology and predictive factors for early and late mortality in Candida bloodstream infections: a population-based surveillance in Spain  M. Puig-Asensio,
CMI readers' survey Clinical Microbiology and Infection
The future of diagnostic bacteriology
Risk factors and clinical outcomes of candidaemia in patients treated for Clostridium difficile infection  A. Russo, M. Falcone, M. Fantoni, R. Murri,
Presentation transcript:

A simple prediction score for estimating the risk of candidaemia caused by fluconazole non-susceptible strains  G. Cuervo, M. Puig-Asensio, C. Garcia-Vidal, M. Fernández-Ruiz, J. Pemán, M. Nucci, J.M. Aguado, M. Salavert, F. González-Romo, J. Guinea, O. Zaragoza, C. Gudiol, J. Carratalà, B. Almirante  Clinical Microbiology and Infection  Volume 21, Issue 7, Pages 684.e1-684.e9 (July 2015) DOI: 10.1016/j.cmi.2015.02.029 Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

Fig. 1 Receiver operating characteristics (ROC) curve for the Flu-NS score in three cohorts: (a) derivation, (b) EUCAST internal validation and (c) external validation. Abbreviations: EUCAST, European Committee on Antimicrobial Susceptibility Testing; Flu-NS, isolates non-susceptible to fluconazole (i.e. those with an MIC ≥4mg/L plus Candida krusei, Candida glabrata and Candida guilliermondii, regardless of their MIC value). Clinical Microbiology and Infection 2015 21, 684.e1-684.e9DOI: (10.1016/j.cmi.2015.02.029) Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions