Trend of Adverse Stage Migration in Patients Treated with Radical Prostatectomy for Localized Prostate Cancer  Felix Preisser, Michele Marchioni, Sebastiano.

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Trend of Adverse Stage Migration in Patients Treated with Radical Prostatectomy for Localized Prostate Cancer  Felix Preisser, Michele Marchioni, Sebastiano Nazzani, Marco Bandini, Zhe Tian, Fred Saad, Raisa S. Pompe, Alberto Briganti, Lars Budäus, Francesco Montorsi, Hartwig Huland, Markus Graefen, Derya Tilki, Pierre I. Karakiewicz  European Urology Oncology  Volume 1, Issue 2, Pages 160-168 (June 2018) DOI: 10.1016/j.euo.2018.03.006 Copyright © 2018 European Association of Urology Terms and Conditions

Fig. 1 Flow diagram showing patient inclusion and exclusion. PSA=prostate-specific antigen. European Urology Oncology 2018 1, 160-168DOI: (10.1016/j.euo.2018.03.006) Copyright © 2018 European Association of Urology Terms and Conditions

Fig. 2 Rate of non–organ-confined prostate cancer (A) unadjusted and (B) adjusted for clinical stage and biopsy Gleason grade group according to the year of diagnosis among patients with clinically localized prostate cancer treated with radical prostatectomy. EAPC=estimated annual percent change; CI=confidence interval. European Urology Oncology 2018 1, 160-168DOI: (10.1016/j.euo.2018.03.006) Copyright © 2018 European Association of Urology Terms and Conditions

Fig. 3 Rate of pathologic primary Gleason ≥4 cancer (A) unadjusted and (B) adjusted for clinical stage and biopsy Gleason grade group according to the year of diagnosis among patients with clinically localized prostate cancer treated with radical prostatectomy. EAPC=estimated annual percent change; CI=confidence interval. European Urology Oncology 2018 1, 160-168DOI: (10.1016/j.euo.2018.03.006) Copyright © 2018 European Association of Urology Terms and Conditions

Fig. 4 Rate of non–organ-confined prostate cancer and/or primary Gleason ≥4 cancer (A) unadjusted and (B) adjusted for clinical stage and biopsy Gleason grade group according to the year of diagnosis among patients with clinically localized prostate cancer treated with radical prostatectomy. EAPC=estimated annual percent change; CI=confidence interval. European Urology Oncology 2018 1, 160-168DOI: (10.1016/j.euo.2018.03.006) Copyright © 2018 European Association of Urology Terms and Conditions