Example of a volumetric capnogram.

Slides:



Advertisements
Similar presentations
Department of Medicine Manipal College of Medical Sciences
Advertisements

Ventilation / Ventilation Control Tests
VENTILATION CHAPTER 4 DR. CARLOS ORTIZ BIO-208. PARTIAL PRESSURES OF RESPIRATORY GASES AIR IS A GAS MIXTURE OF MOSTLY N 2 AND O 2. THIS TRACES OF ARGON,
Transport of gases in the blood.   Gas exchange between the alveolar air and the blood in pulmonary capillaries results in an increased oxygen concentration.
Copyright © 2008 Thomson Delmar Learning CHAPTER 8 Ventilation-Perfusion Relationships.
Human Physiology Respiratory System
Effect on production of reactive oxygen species (ROS) by polymorphonuclear cells (PMN) from healthy and CF donors on treatment with different sizes of.
TOTAL PULMONARY VENTILATION
Receiver operator characteristic (ROC) curves comparing the ability of different expiratory breathing parameters and perinatal variables (birthweight z-score.
Echocardiography view
Mouth pressure (Pmo), flow rate and mean arterial blood pressure (Pa) data during a single lung volume recruitment manoeuvre in representative subjects.
Flowchart for calculating the relative risk (RR) for cancer X and lung cancer (LC). Flowchart for calculating the relative risk (RR) for cancer X and lung.
Kaplan–Meier curves of 12-month survival after an index chronic obstructive pulmonary disease-related hospitalisation according to level of moderate and.
Distribution of forced expiratory volume in 1 s (FEV1) relative to Global Lung Function Initiative reference values (GLI2012) [10] expressed as FEV1 %
Prevalence of true-positive, false-negative and false-positive cases of chronic obstructive pulmonary disease identified with the fixed-limit Global Initiative.
Bland–Altman plots of in vitro functional residual capacity (FRC) measurements on each device. Bland–Altman plots of in vitro functional residual capacity.
Flow diagram summarising the most important effects of biochemical (left) and mechanical (right) pregnancy-induced factors on pulmonary function, ventilatory.
Comparison of the characteristics at first enrolment for United Network for Organ Sharing (UNOS) patients (n=8315) and virtual patients (n=2 048 784).
Survival without tracheostomy
Kaplan–Meier curve for the time until the development of lung cancer in patients with idiopathic pulmonary fibrosis. Kaplan–Meier curve for the time until.
The 3-compartment lung model described by Riley and Cournand151,152 represents gas exchange in the lung in regard to the matching of alveolar gas volume.
Distribution of lower extremity artery disease (LEAD) Fontaine stages over the combined chronic obstructive pulmonary disease (COPD) Global Initiative.
Bland–Altman plot of slopes of measurement 1 versus 2
Bland–Altman comparison of lung clearance index (LCI) from multiple breath wash-out following open and modified closed circuit wash-in for both healthy.
Severe pulmonary hypertension (PH) in interstitial lung disease (ILD) stepwise composite echocardiographic score. Severe pulmonary hypertension (PH) in.
Lung histopathology from two subjects demonstrating either capillaritis or prior alveolar haemorrhage. Lung histopathology from two subjects demonstrating.
Kaplan–Meier survival curves of all-cause mortality in patients with idiopathic pulmonary fibrosis (IPF). Kaplan–Meier survival curves of all-cause mortality.
Nitrogen concentration curve at the end of the washout from a nitrogen multiple-breath washout measurement in a patient with primary ciliary dyskinesia.
Capnogram slope and ventilation dead space parameters: comparison of mainstream and sidestream techniques  A.L. Balogh, F. Petak, G.H. Fodor, J. Tolnai,
Discriminatory performance (receiver operating characteristics (ROC) analysis) of lung clearance index (LCI) analysed with the different methods. a) ROC.
A white elephant or the elephant in the room
The linear interpolation analysis and the fitting-curve analysis give lower values for lung clearance index (LCI). a) Bland–Altman plots of the absolute.
Change in lung clearance index (LCI) (mean±sd % change lung turnovers compared with baseline) based on modelled a, b) continuous and c, d) isolated pre-capillary.
Effects of alveolar dead-space, shunt and V ˙ / Q ˙ distribution on respiratory dead- space measurements  Y. Tang, M.J. Turner, A.B. Baker  British Journal.
Impact of immunosuppressive therapy on pulmonary function, recurrence of diffuse alveolar haemorrhage (DAH) and chest computed tomography (CT) findings.
Kaplan–Meier curves of long-term survival in young (
The variability of probability of that the length of stay is longer than the median by country. The variability of probability of that the length of stay.
A) Overview of a nitrogen multiple-breath washout measurement in LungSim (NM GmbH); the crosses represent the end-tidal nitrogen concentration per breath,
Cardiopulmonary exercise testing of a patient with chronic thromboembolic pulmonary hypertension showing fields 4, 6 and 9 of the Wasserman panel. a) Elevated.
Selection of patients: 248 consecutive patients with newly diagnosed pre-capillary pulmonary hypertension were included in the study. Selection of patients:
Average mean arterial pressure (Pa) during lung volume recruitment (LVR) in (a) the respiratory muscle weakness (RMW) group and (b) the control group.
Systems biology as a tool to improve idiopathic pulmonary fibrosis (IPF) treatment effectiveness. Systems biology as a tool to improve idiopathic pulmonary.
Flow–volume loop analysis
a) Mortality per time point (p<0
Scatter plot of the % change versus baseline in pulmonary function test results at a) 4 months and b) the end of the study versus the analyte concentration.
A family-based pulmonary rehabilitation (PR) programme enhanced the coping resources of the families of chronic obstructive pulmonary disease patients.
The regression lines between the asynchrony index (AI) and the double true index (DTI) shown for overall data, and for mask and helmet separately. The.
A) Cumulative count and b) percent cumulative use of the different pulmonary function test (PFT) measures as longitudinal outcomes for systemic sclerosis-associated.
Receiver operating characteristic (ROC) curves (area under the curve (AUC) (95% CI)) for FACED (forced expiratory volume in 1 s, age, chronic colonisation.
The minute ventilation (V′E)/carbon dioxide production (V′CO2) relationship slope in a patient with pulmonary arterial hypertension and preserved physiological.
Oxygen uptake and carbon dioxide removal in the membrane lung
Physician perspectives on the most useful methods for monitoring α1-antitrypsin deficiency in the clinical trial setting versus clinical practice. Physician.
Management of patients with obesity hypoventilation syndrome (OHS) from diagnosis to integrated care to modify health trajectories. Management of patients.
Differences in a) functional residual capacity (FRC) and b) lung clearance index (LCI) when using all trials in comparison with only the first two trials.
Scatter plot of body mass index (BMI) versus forced expiratory volume in the first second (FEV1), and linear correlation lines for normal spirometry and.
Forest plot of the a) sensitivity and b) specificity of different pulmonary function test screening algorithms for the presence of systemic sclerosis-associated.
Distribution of patients in the first- or second-year follow-up according to the number of acute exacerbations of chronic obstructive pulmonary disease.
Mean pulmonary arterial pressure (Ppa) as a function of cardiac output (Q) at two different levels of pulmonary vascular resistance (PVR). Mean pulmonary.
Correlation between inspiratory capacity (IC)/total lung capacity (TLC) ratio and oxygen pulse at peak exercise in chronic obstructive pulmonary disease.
Marco Guazzi et al. JACC 2017;70:
Alveolar and airway CO2 during the ventilatory cycle: flow (upper graph) and mean alveolar and airway CO2 pressure scalars (lower graph). Alveolar and.
Graphical representation of physiologic dead space fraction determined by volumetric capnography, using the approaches of Bohr and Enghoff, which shows.
Distribution of diffusing capacity of the lung for carbon monoxide (DLCO) among 243 scleroderma patients who underwent right heart catheterisation (RHC)
Progression in the patient’s pulmonary function tests from 2010 to a) Forced vital capacity (FVC); b) total lung capacity (TLC); c) diffusing capacity.
Current practice on the suspicion of respiratory muscle dysfunction (especially of the diaphragm), outside the intensive care setting. Current practice.
A–f) Diaphragm electromyography (EMGdi) and selected ventilatory and indirect gas exchange responses to incremental cycle exercise test in patients with.
Depiction of an expiratory flow curve.
A: Representation of a volumetric capnogram with a schematic approach for the measurement of dead space. A: Representation of a volumetric capnogram with.
The 3 compartment lung model described by Riley36,37 represents gas exchange in the lung in regards to the matching of alveolar ventilation (V̇A) and perfusion.
Tracing of tidal breathing followed by an inspiratory manoeuvre to total lung capacity (TLC) to record inspiratory capacity (IC), followed by a full expiration.
Presentation transcript:

Example of a volumetric capnogram. Example of a volumetric capnogram. A linear approximation of phase 3 of the capnogram (slope 3) is indicated by the dotted line. Carbon dioxide production (VCO2) can be calculated by dividing the area under the curve (AUC) of the capnogram (indicated by the grey area) by the atmospheric pressure. Arterial carbon dioxide tension (PaCO2) is indicated by the dashed line. Capnography variables were defined as follows: volumetric capnography parameter (CapNoPE)=(VCO2×slope 3)/RR; pulmonary embolism index (PE-index)=(PaCO2–PETCO2)/slope 3; late dead-space fraction (Fdlate)=1–(extrapolated PCO2 at 15% of TLC/PaCO2); alveolar dead-space fraction (AVDSf)=(PaCO2–PETCO2)/PaCO2. RR: respiratory rate; PETCO2: end-tidal carbon dioxide tension; PCO2: carbon dioxide tension; TLC: total lung capacity Timon M. Fabius et al. ERJ Open Res 2018;4:00099-2018 ©2018 by European Respiratory Society