Endoscopic submucosal dissection of an esophageal granular cell tumor

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Presentation transcript:

Endoscopic submucosal dissection of an esophageal granular cell tumor Richard F. Knoop, MD, Arthur Schmidt, MD, Gian Kayser, MD, Robert Thimme, MD, Andreas Fischer, MD VideoGIE Volume 4, Issue 2, Pages 58-61 (February 2019) DOI: 10.1016/j.vgie.2018.10.015 Copyright © 2018 American Society for Gastrointestinal Endoscopy Terms and Conditions

Figure 1 Gastroesophageal junction with granular cell tumor (star). VideoGIE 2019 4, 58-61DOI: (10.1016/j.vgie.2018.10.015) Copyright © 2018 American Society for Gastrointestinal Endoscopy Terms and Conditions

Figure 2 EUS view of the esophageal granular cell tumor showing a well-defined tumor (calipers) strictly limited to the submucosa. VideoGIE 2019 4, 58-61DOI: (10.1016/j.vgie.2018.10.015) Copyright © 2018 American Society for Gastrointestinal Endoscopy Terms and Conditions

Figure 3 The target lesion is circularly marked. VideoGIE 2019 4, 58-61DOI: (10.1016/j.vgie.2018.10.015) Copyright © 2018 American Society for Gastrointestinal Endoscopy Terms and Conditions

Figure 4 Specimen of granular cell tumor completely resected by endoscopic submucosal dissection. VideoGIE 2019 4, 58-61DOI: (10.1016/j.vgie.2018.10.015) Copyright © 2018 American Society for Gastrointestinal Endoscopy Terms and Conditions

Figure 5 Histologic images of the granular cell tumor. A, Within the submucosa, a delicately demarcated proliferation of monomorphous cells with eosinophilic granular cytoplasm (H&E, orig. mag. ×5). B, Cells are immunohistochemically positive for S100, verifying it as granular cell tumor (S100, orig. mag. ×40). VideoGIE 2019 4, 58-61DOI: (10.1016/j.vgie.2018.10.015) Copyright © 2018 American Society for Gastrointestinal Endoscopy Terms and Conditions

Figure 6 After 4 weeks: regular scar without signs of stenosis (star). Polypous postresection granulation tissue (cross). Additionally, short tongues of Barrett’s epithelia are recognized (arrow). VideoGIE 2019 4, 58-61DOI: (10.1016/j.vgie.2018.10.015) Copyright © 2018 American Society for Gastrointestinal Endoscopy Terms and Conditions