Cutaneous spindle cell carcinoma misdiagnosed as atypical fibroxanthoma based on immunohistochemical stains Anastasia Benoit, MD, Joshua Wisell, MD,

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Presentation transcript:

Cutaneous spindle cell carcinoma misdiagnosed as atypical fibroxanthoma based on immunohistochemical stains Anastasia Benoit, MD, Joshua Wisell, MD, Mariah Brown, MD JAAD Case Reports Volume 1, Issue 6, Pages 392-394 (November 2015) DOI: 10.1016/j.jdcr.2015.09.003 Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Invasive spindle cell proliferation with hematoxylin-eosin stain. (Original magnification: ×10.) JAAD Case Reports 2015 1, 392-394DOI: (10.1016/j.jdcr.2015.09.003) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Negative IHC staining with pan-cytokeratin (AE1/AE3). (Original magnification: ×20.) JAAD Case Reports 2015 1, 392-394DOI: (10.1016/j.jdcr.2015.09.003) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 3 Clinical photograph of the tumor at the time of MMS. Note the small, skin-colored papules on the chest wall inferior to the tumor. JAAD Case Reports 2015 1, 392-394DOI: (10.1016/j.jdcr.2015.09.003) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 4 Positive IHC staining for HMWK (34betaE12). (Original magnification: ×20.) JAAD Case Reports 2015 1, 392-394DOI: (10.1016/j.jdcr.2015.09.003) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions