Pulmonary Kirsten Rat Sarcoma Virus Mutation Positive Mucinous Adenocarcinoma Arising in a Congenital Pulmonary Airway Malformation, Mixed Type 1 and.

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Pulmonary Kirsten Rat Sarcoma Virus Mutation Positive Mucinous Adenocarcinoma Arising in a Congenital Pulmonary Airway Malformation, Mixed Type 1 and 2 Gopal Singh, MD, Amy Coffey, MD, Robert Neely, MD, Daniel Lambert, BS, Joshua Sonett, MD, Alain C. Borczuk, MD, Lyall Gorenstein, MD The Annals of Thoracic Surgery Volume 102, Issue 4, Pages e335-e337 (October 2016) DOI: 10.1016/j.athoracsur.2016.01.104 Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 (A, B) Axial computed tomography scans of the chest of this patient with multiple cysts in the right upper lobe. The Annals of Thoracic Surgery 2016 102, e335-e337DOI: (10.1016/j.athoracsur.2016.01.104) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 (A) Low-power view shows a large predominant cyst characteristic of type 1 congenital pulmonary airway malformation with multiple surrounding smaller cysts lined by bronchiolar-type epithelium, more typical of type 2 (hematoxylin and eosin, ×20). (B) Intracystic mucinous proliferation arising in the predominant cyst (hematoxylin and eosin, ×200). (C, D) Extracystic mucinogenic proliferation composed of back-to-back glands, consistent with mucinous adenocarcinoma arising in the background of CPAM. The Annals of Thoracic Surgery 2016 102, e335-e337DOI: (10.1016/j.athoracsur.2016.01.104) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions