Asymmetric Mechanical Properties of Porcine Aortic Sinuses

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Asymmetric Mechanical Properties of Porcine Aortic Sinuses Namrata Gundiah, PhD, Kimberly Kam, BS, Peter B. Matthews, BS, Julius Guccione, PhD, Harry A. Dwyer, PhD, David Saloner, PhD, Timothy A.M. Chuter, MD, T. Sloane Guy, MD, Mark B. Ratcliffe, MD, Elaine E. Tseng, MD  The Annals of Thoracic Surgery  Volume 85, Issue 5, Pages 1631-1638 (May 2008) DOI: 10.1016/j.athoracsur.2008.01.035 Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Schematic of the aortic root showing the locations from which the tissues were excised for mechanical experiments. (L. = left; LC = left coronary sinus; NC = noncoronary sinus; R. = right; RC = right coronary sinus; x axis = circumferential; y axis = longitudinal.) The Annals of Thoracic Surgery 2008 85, 1631-1638DOI: (10.1016/j.athoracsur.2008.01.035) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Custom-built biaxial stretcher used in the experiments. The Annals of Thoracic Surgery 2008 85, 1631-1638DOI: (10.1016/j.athoracsur.2008.01.035) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Cauchy stress (Txx, Tyy) versus Green strain (Exx, Eyy) curves for the left coronary sinus (top), right coronary sinus (middle), and noncoronary sinus (bottom) tissues in the study, constructed using the coefficients to the Fung strain energy function obtained by the Levenberg-Marquardt optimization method. The Annals of Thoracic Surgery 2008 85, 1631-1638DOI: (10.1016/j.athoracsur.2008.01.035) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Sample 15 from a noncoronary sinus. The principal strains in x and y directions as well as shear strains were calculated from the four triangles. Strains were similar for all four triangles, demonstrating mostly homogeneous deformation. The Annals of Thoracic Surgery 2008 85, 1631-1638DOI: (10.1016/j.athoracsur.2008.01.035) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 Composite Cauchy stress curves (Txx, Tyy) for the left coronary sinus (LC), the right coronary sinus (RC), and the noncoronary (NC) sinus tissues in the study. Each individual curve is constructed using the average value of the coefficients to the strain energy function, as shown in Table 1. The Annals of Thoracic Surgery 2008 85, 1631-1638DOI: (10.1016/j.athoracsur.2008.01.035) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 6 Tissue stiffness computed at a Green strain of 0.3, comparing (A) left coronary sinus (LC), the right coronary sinus (RC), and the noncoronary (NC) sinus stiffness, and (B) longitudinal versus circumferential stiffness for each sinus. The Annals of Thoracic Surgery 2008 85, 1631-1638DOI: (10.1016/j.athoracsur.2008.01.035) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions