Advanced Parkinson Disease: Are We Breaking New Ground?

Program Overview

Progression of PD

Motor and Non-Motor Symptoms in PD

Non-Motor Features of PD Affect the Whole Body

Non-Motor Symptoms in PD: Advanced Stages

Most Troublesome Symptoms in Advanced PD: The Patient's Perspective

Non-Motor Symptoms: Correlation of QoL Measures

Progression to Advanced PD

Increased Motor Severity And Increased Costs Related to Loss of Independence

Increase in Wearing-Off Motor Symptoms With Disease Duration: Negative Impact on QoL

Evolution From Early to Advanced PD Based on Changes in Levodopa Response

Pharmacokinetics of Levodopa and Delayed Gastric Emptying in PD

Adjunct Therapies to Levodopa: Evidence-Based Review

Device-Aided Therapies in PD

Multicenter Comparative Observational Study of Apomorphine and Levodopa Infusion in PD: EuroInf

GLORIA Registry: Levodopa-Carbidopa Intestinal Gel in Advanced PD

Effects of Bilateral Subthalamic Stimulation on Non-Motor Symptoms in PD

Summary of Device-Aided Approaches

Patient Profiles for Good Candidates for Device-Aided Treatments: Consensus Panel

Impulse Control Disorders and Infusion Treatment: EuroInf

Patient Behavior on Device-Aided Therapies Can Be Difficult to Predict

Role of Infusion Therapies for Advanced Age and Palliative Care

Clinician Perspective on Infusion Use in Nursing Home Setting: Patients With Cognitive Decline

Device-Aided Therapy: Role of the Caregiver

Caregiver Burden With Infusion Therapy

Recommendations for Informing Patients and Caregivers About Device-Aided Therapy: Consensus Report

Concluding Remarks (I)

Concluding Remarks (II)

Abbreviations

Abbreviations (cont)