Prognostic Impact of the Findings on Thin-Section Computed Tomography in Patients with Subcentimeter Non–Small Cell Lung Cancer Aritoshi Hattori, MD,

Slides:

Advertisements

Similar presentations

Kazuma Nagata, MD, Reiko Kaji, MD, Keisuke Tomii, MD

Advertisements

Prognostic impacts of EGFR mutation status and subtype in patients with surgically resected lung adenocarcinoma Kazuya Takamochi, MD, Shiaki Oh, MD,

Jeffrey Bradley, MD Journal of Thoracic Oncology

Approach to the Ground-Glass Nodule

Which is the Better Prognostic Factor for Resected Non-small Cell Lung Cancer: The Number of Metastatic Lymph Nodes or the Currently Used Nodal Stage.

Sequential Immunologic Reactions after Suspension of Nivolumab Treatment in Lung Adenocarcinoma Patient Hiromichi Shirasu, MD, Akira Ono, MD, Toshiaki.

Successful Osimertinib Rechallenge in a Patient with T790M-Mutant Non–Small Cell Lung Cancer after Osimertinib-Induced Interstitial Lung Disease Eisaku.

Characteristics and outcomes of secondary nodules identified on initial computed tomography scan for patients undergoing resection for primary non–small.

Prognostic Significance of the Number of Lymph Nodes Removed at Lobectomy in Stage IA Non-small Cell Lung Cancer Sai-Hong Ignatius Ou, MD, PhD, Jason.

Effect of tumor size on prognosis in patients with non–small cell lung cancer: The role of segmentectomy as a type of lesser resection Morihito Okada,

Mark F. Berry, MD, Thomas A. Sporn, MD, Joseph O. Moore, MD, Thomas A

A Case of Concurrent De Novo C797S and L858R EGFR Mutation Detected in Stage IA Non–Small Cell Lung Cancer Patient Jong Sik Lee, MD, Jae Young Hur, PhD,

Radiographically determined noninvasive adenocarcinoma of the lung: Survival outcomes of Japan Clinical Oncology Group 0201 Hisao Asamura, MD, Tomoyuki.

Long-Term Follow-up of Small Pulmonary Ground-Glass Nodules Stable for 3 Years: Implications of the Proper Follow-up Period and Risk Factors for Subsequent.

Validation of the Stage Groupings in the Eighth Edition of the TNM Classification for Lung Cancer Xizhao Sui, MD, Wei Jiang, MD, Haiqing Chen, MD, Fan.

Impact of tumor size on outcomes after anatomic lung resection for stage 1A non–small cell lung cancer based on the current staging system Shamus R.

Prognostic Value of Primary Tumor Volume Changes on kV-CBCT during Definitive Chemoradiotherapy for Stage III Non–Small Cell Lung Cancer Patrick Wald,

Susan C. Scott, MD, Nathan A. Pennell, MD, PhD

Prognostic Impact of Margin Distance and Tumor Spread Through Air Spaces in Limited Resection for Primary Lung Cancer Kyohei Masai, MD, Hiroyuki Sakurai,

Tetsuya Mitsudomi, MD, Hirohito Tada, MD Journal of Thoracic Oncology

IA05.01 Lung Cancer Cases Journal of Thoracic Oncology

Neither Maximum Tumor Size nor Solid Component Size Is Prognostic in Part-Solid Lung Cancer: Impact of Tumor Size Should Be Applied Exclusively to Solid.

Importance of Ground Glass Opacity Component in Clinical Stage IA Radiologic Invasive Lung Cancer Aritoshi Hattori, MD, Takeshi Matsunaga, MD, Kazuya.

Oncological Characteristics of Radiological Invasive Adenocarcinoma with Additional Ground-Glass Nodules on Initial Thin-Section Computed Tomography:

Prognostic Factors in Completely Resected Node-Negative Lung Adenocarcinoma of 3 cm or Smaller Jung-Jyh Hung, MD, PhD, Yi-Chen Yeh, MD, Yu-Chung Wu,

Turning Gray: The Natural History of Lung Cancer Over Time

Which is the Better Prognostic Factor for Resected Non-small Cell Lung Cancer: The Number of Metastatic Lymph Nodes or the Currently Used Nodal Stage.

Central versus Peripheral Tumor Location: Influence on Survival, Local Control, and Toxicity Following Stereotactic Body Radiotherapy for Primary Non–Small-Cell.

Clinicopathologic Features of Resected Subcentimeter Lung Cancer

How Long Should Small Lung Lesions of Ground-Glass Opacity be Followed? Yoshihisa Kobayashi, MD, Takayuki Fukui, MD, Simon Ito, MD, Noriyasu Usami, MD,

Lung Cancer with Localized Ground-Glass Attenuation Represents Early-Stage Adenocarcinoma in Nonsmokers Nobuhiko Seki, MD, Shigeki Sawada, MD, Masao.

Mediastinal Lymph Node Examination and Survival in Resected Early-Stage Non– Small-Cell Lung Cancer in the Surveillance, Epidemiology, and End Results.

Lung Adenocarcinomas Manifesting as Radiological Part-Solid Nodules Define a Special Clinical Subtype Ting Ye, MD, PhD, Lin Deng, MD, Shengping Wang,

Tumor-Infiltrating Foxp3+ Regulatory T Cells are Correlated with Cyclooxygenase-2 Expression and are Associated with Recurrence in Resected Non-small.

LAG-3 Protein Expression in Non–Small Cell Lung Cancer and Its Relationship with PD- 1/PD-L1 and Tumor-Infiltrating Lymphocytes Yayi He, MD, PhD, Hui.

A clinicopathological study of resected subcentimeter lung cancers: a favorable prognosis for ground glass opacity lesions Hisao Asamura, MD, Kenji Suzuki,

Are There Imaging Characteristics Associated with Epidermal Growth Factor Receptor and KRAS Mutations in Patients with Adenocarcinoma of the Lung with.

Radiologic Classification of Small Adenocarcinoma of the Lung: Radiologic-Pathologic Correlation and Its Prognostic Impact Kenji Suzuki, MD, Masahiko.

PD-L1 as a Companion Biomarker for Immune Checkpoint Inhibitors in NSCLC: Should RNA ISH (RISH) Be Considered? Steven G. Gray, PhD Journal of Thoracic.

Impact of positive pleural lavage cytology on survival in patients having lung resection for non–small-cell lung cancer: An international individual patient.

Frequency of Lymph Node Metastasis According to the Size of Tumors in Resected Pulmonary Adenocarcinoma with a Size of 30 mm or Smaller Yangki Seok,

Nivolumab-Induced Acute Diabetes Mellitus and Hypophysitis in a Patient with Advanced Pulmonary Pleomorphic Carcinoma with a Prolonged Tumor Response

Elizabeth Cathcart-Rake, MD, Ariel Lopez-Chavez, MD, MS

Vamsidhar Velcheti, MD Journal of Thoracic Oncology

Jennifer L. Dallas, MD, Michael A. Jantz, MD, Judith L

Management of Ground-Glass Opacity Lesions Detected in Patients with Otherwise Operable Non-small Cell Lung Cancer Hong Kwan Kim, MD, Yong Soo Choi,

Jeffrey Bradley, MD Journal of Thoracic Oncology

The Prognostic Impact of Cigarette Smoking on Patients with Non-small Cell Lung Cancer Ryo Maeda, MD, Junji Yoshida, MD, PhD, Genichiro Ishii, MD, PhD,

Clinical Relevance of Our Multimodality Prognostic Score

It’s All in the “Swerve of the Curve”

“Early” peripheral lung cancer: prognostic significance of ground glass opacity on thin- section computed tomographic scan Kenji Suzuki, MD, Hisao Asamura,

Immune-Modulating Vaccines in Non-small Cell Lung Cancer

Maintenance Therapy and Advanced Non–Small-Cell Lung Cancer: A Skeptic's View Martin J. Edelman, MD, Thierry Le Chevalier, MD, Jean-Charles Soria, MD,

Two Generations of Light/Never-Smokers With Advanced Adenocarcinoma of the Lung with Durable Responses to Erlotinib Nathan A. Pennell, MD, PhD, Lihong.

Primary Tumor Standardized Uptake Value Measured on F18-Fluorodeoxyglucose Positron Emission Tomography Is of Prediction Value for Survival and Local.

Clinical and Pathological Staging Validation in the Eighth Edition of the TNM Classification for Lung Cancer: Correlation between Solid Size on Thin-Section.

The Clinical Impact of Solid and Micropapillary Patterns in Resected Lung Adenocarcinoma Naoki Yanagawa, MD, PhD, Satoshi Shiono, MD, PhD, Masami Abiko,

Influence of Ground Glass Opacity and the Corresponding Pathological Findings on Survival in Patients with Clinical Stage I Non–Small Cell Lung Cancer

APLCC POSTER SESSION 2 - WEDNESDAY, NOVEMBER 28

Aritoshi Hattori, MD, Kenji Suzuki, MD

Prognostic Role of Positron Emission Tomography and High-Resolution Computed Tomography in Clinical Stage IA Lung Adenocarcinoma Hirofumi Uehara, MD,

A clinicopathological study of resected adenocarcinoma 2 cm or less in diameter Norihiko Ikeda, MD, PhD, Junichi Maeda, MD, Koichi Yashima, MD, Masahiro.

Who should decide margin length in pulmonary excision of lung cancer?

Effect of Tumor Size on Prognosis in Patients Treated with Radical Radiotherapy or Chemoradiotherapy for Non–Small Cell Lung Cancer: An Analysis of the.

Razvan Diaconescu, MD, Chantal Lafond, MD, Renaud Whittom, MD

Visceral Pleural Invasion Is Not a Significant Prognostic Factor in Patients With a Part- Solid Lung Cancer Aritoshi Hattori, MD, Kenji Suzuki, MD, Takeshi.

Robert Comis, MD, The Passing of a “Lung Man”

Circulating Tumor Cells Detected in the Tumor-Draining Pulmonary Vein Are Associated with Disease Recurrence after Surgical Resection of NSCLC Phil A.J.

Prognostic Significance of Tumor Size in Patients with Stage III Non–Small-Cell Lung Cancer: A Surveillance, Epidemiology, and End Results (SEER) Survey.

Reply to “Influence of Body Mass Index on Overall Survival Following Surgical Resection of Non–Small Cell Lung Cancer: Methodological Issues” Boris Sepesi,

Presentation transcript:

Prognostic Impact of the Findings on Thin-Section Computed Tomography in Patients with Subcentimeter Non–Small Cell Lung Cancer Aritoshi Hattori, MD, Takeshi Matsunaga, MD, Takuo Hayashi, MD, Kazuya Takamochi, MD, Shiaki Oh, MD, Kenji Suzuki, MD Journal of Thoracic Oncology Volume 12, Issue 6, Pages 954-962 (June 2017) DOI: 10.1016/j.jtho.2017.02.015 Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

Figure 1 Typical findings of subcentimeter NSCLC are presented on the basis of the findings of thin-section computed tomography (CT) scan. Pure ground glass opacity (GGO) tumor was defined as a lung tumor without a solid component (i.e., CTR = 0) and part solid tumor was defined as a lung tumor with both a GGO and solid component (i.e., 0＜CTR＜1.0), whereas pure solid tumor was defined as a tumor showing only consolidation without GGO on thin-section CT (i.e., consolidation-to-tumor ratio [CTR] = 1.0). Journal of Thoracic Oncology 2017 12, 954-962DOI: (10.1016/j.jtho.2017.02.015) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

Figure 2 The overall survival (OS) and recurrence-free survival (RFS) of 328 patients with c-N0 subcentimeter NSCLC are demonstrated. The 5-year OS and RFS rates were extremely better in patients with a pure ground glass opacity (GGO) (OS and RFS = 100%) or part solid (OS = 97.5%, RFS = 94.9%) tumor, whereas those of patients with pure solid subcentimeter NSCLC were 87.6% and 79.3% (OS: p = 0.0015; RFS: p < 0.0001), respectively. Journal of Thoracic Oncology 2017 12, 954-962DOI: (10.1016/j.jtho.2017.02.015) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

Figure 3 Locoregional recurrence-free survival (RFS) according to the operative modes was demonstrated in patients with radiologically determined part solid or pure solid subcentimeter NSCLC. A marginal difference was observed between the two study arms, and the 5-year locoregional RFS was 92.3% for the anatomical resection arm but 86.2% for the wedge resection arm (p = 0.0718). Journal of Thoracic Oncology 2017 12, 954-962DOI: (10.1016/j.jtho.2017.02.015) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions