Lung adenocarcinoma with intraoperatively diagnosed pleural seeding: Is main tumor resection beneficial for prognosis? Chi Li, MD, Shuenn-Wen Kuo, MD,

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Presentation transcript:

Lung adenocarcinoma with intraoperatively diagnosed pleural seeding: Is main tumor resection beneficial for prognosis? Chi Li, MD, Shuenn-Wen Kuo, MD, Hsao-Hsun Hsu, MD, PhD, Mong-Wei Lin, MD, PhD, Jin-Shing Chen, MD, PhD The Journal of Thoracic and Cardiovascular Surgery Volume 155, Issue 3, Pages 1238-1249.e1 (March 2018) DOI: 10.1016/j.jtcvs.2017.09.162 Copyright © 2017 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 A, Thoracoscopic view of the right upper lobe main tumor (arrow). B, Thoracoscopic view of localized pleural seeding (arrow) located on the lower chest wall near the reflection of the diaphragm. The Journal of Thoracic and Cardiovascular Surgery 2018 155, 1238-1249.e1DOI: (10.1016/j.jtcvs.2017.09.162) Copyright © 2017 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Kaplan–Meier survival curves of progression-free survival (A) and overall survival (B) of the study groups. The Journal of Thoracic and Cardiovascular Surgery 2018 155, 1238-1249.e1DOI: (10.1016/j.jtcvs.2017.09.162) Copyright © 2017 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Patterns of disease progression. A, Time from surgery to detection of local progression. B, Time from surgery to detection of regional progression. C, Time from surgery to detection of distant metastasis. The Journal of Thoracic and Cardiovascular Surgery 2018 155, 1238-1249.e1DOI: (10.1016/j.jtcvs.2017.09.162) Copyright © 2017 The American Association for Thoracic Surgery Terms and Conditions

Figure E1 Pleurectomy was performed after the surgeon regarded the pleural metastasis as completely resectable. A, Thoracoscopic view of the right upper lobe main tumor and pleural metastasis (arrows). Although there were more than 3 pleural nodules and the patient was thus considered to have diffused pleural metastasis, these grossly visible nodules were located in the same area and could be completely resectable. B, Parietal pleura after video-assisted thoracoscopic surgery pleurectomy. The Journal of Thoracic and Cardiovascular Surgery 2018 155, 1238-1249.e1DOI: (10.1016/j.jtcvs.2017.09.162) Copyright © 2017 The American Association for Thoracic Surgery Terms and Conditions

Figure E2 Kaplan–Meier survival curves of progression-free survival (A) and overall survival (B) of patients based on surgical method. The Journal of Thoracic and Cardiovascular Surgery 2018 155, 1238-1249.e1DOI: (10.1016/j.jtcvs.2017.09.162) Copyright © 2017 The American Association for Thoracic Surgery Terms and Conditions

Survival was superior in the tumor resection group compared with the open-close group. The Journal of Thoracic and Cardiovascular Surgery 2018 155, 1238-1249.e1DOI: (10.1016/j.jtcvs.2017.09.162) Copyright © 2017 The American Association for Thoracic Surgery Terms and Conditions

Video 1 Dr Mong-Wei Lin explaining the importance of the work to the readers of the journal and the community of thoracic surgeons worldwide. Video available at: http://www.jtcvsonline.org/article/S0022-5223(17)32730-7/fulltext. The Journal of Thoracic and Cardiovascular Surgery 2018 155, 1238-1249.e1DOI: (10.1016/j.jtcvs.2017.09.162) Copyright © 2017 The American Association for Thoracic Surgery Terms and Conditions

The Journal of Thoracic and Cardiovascular Surgery 2018 155, 1238-1249 The Journal of Thoracic and Cardiovascular Surgery 2018 155, 1238-1249.e1DOI: (10.1016/j.jtcvs.2017.09.162) Copyright © 2017 The American Association for Thoracic Surgery Terms and Conditions