Preoperative heart rate and myocardial injury after non-cardiac surgery: results of a predefined secondary analysis of the VISION study T.E.F. Abbott,

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Presentation transcript:

Preoperative heart rate and myocardial injury after non-cardiac surgery: results of a predefined secondary analysis of the VISION study T.E.F. Abbott, G.L. Ackland, R.A. Archbold, A. Wragg, E. Kam, T. Ahmad, A.W. Khan, E. Niebrzegowska, R.N. Rodseth, P.J. Devereaux, R.M. Pearse British Journal of Anaesthesia Volume 117, Issue 2, Pages 172-181 (August 2016) DOI: 10.1093/bja/aew182 Copyright © 2016 The Author(s) Terms and Conditions

Fig 1 Patient flow diagram showing the number of patients included and excluded from each analysis. British Journal of Anaesthesia 2016 117, 172-181DOI: (10.1093/bja/aew182) Copyright © 2016 The Author(s) Terms and Conditions

Fig 2 Forest plot showing the odds ratios for myocardial injury, myocardial infarction, and mortality by each heart rate (HR) decile (in beats per minute), with 95% confidence intervals. The odds ratios for myocardial injury are as follows: HR <60, 0.92 (0.76–1.14); HR 60–64, 0.86 (0.69–1.06); HR 65–68, 0.88 (0.71–1.09); HR 69–71, 1.01 (0.82–1.26); HR 72–74, 0.71 (0.55–0.91); HR 75–79, 0.88 (0.73–1.07); HR 80–82, 1.01 (0.83–1.24); HR 83–87, 1.36 (1.11–1.66); HR 88–96, 1.11 (0.93–1.32); and HR >96, 1.48 (1.23–177). The odds ratios for myocardial infarction are as follows: HR <60, 0.89 (0.64–1.23); HR 60–64, 0.72 (0.51–1.01); HR 65–68, 0.99 (0.72–1.36); HR 69–71, 1.21 (0.89–1.64); HR 72–74, 0.74 (0.50–1.09); HR 75–79, 1.04 (0.79–1.37); HR 80–82, 0.97 (0.72–1.32); HR 83–87, 1.12 (0.82–1.54); HR 88–96, 0.92 (0.70–1.21); and HR >96, 1.71 (1.34–2.18). The odds ratios for mortality are as follows: HR <60, 0.50 (0.29–0.88); HR 60–64, 0.71 (0.45–1.13); HR 65–68, 0.61 (0.37–1.02); HR 69–71, 1.07 (0.71–1.63); HR 72–74, 0.70 (0.42–1.17); HR 75–79, 1.12 (0.79–1.58); HR 80–82, 1.11 (0.76–1.62); HR 83–87, 1.06 (0.70–1.61); HR 88–96, 1.46 (1.08–1.97); and HR >96, 3.16 (2.45–4.07). British Journal of Anaesthesia 2016 117, 172-181DOI: (10.1093/bja/aew182) Copyright © 2016 The Author(s) Terms and Conditions

Fig 3 Plot of the fractional polynomial logistic regression model. The x-axis shows heart rate, and the y-axis is the probability of myocardial injury after non-cardiac surgery (MINS) within 30 days of surgery. British Journal of Anaesthesia 2016 117, 172-181DOI: (10.1093/bja/aew182) Copyright © 2016 The Author(s) Terms and Conditions