THE DIABETES HEALTH PROFILE (DHP) DEVELOPMENT JOURNEY 1986 Initial development of the DHP-1 Patient input 25 In-depth patient interviews Literature review.

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THE DIABETES HEALTH PROFILE (DHP) DEVELOPMENT JOURNEY 1986 Initial development of the DHP-1 Patient input 25 In-depth patient interviews Literature review + DHP Conceptual model The DHP-1 and DHP-18 are standardised diabetes-specific measures of the impact of diabetes on psychological and behavioural dysfunctioning in Type 1 and Type 2 diabetes respectively. Compliant with FDA guidelines on PRO developments for label claims.

Through a combination of factor analyses, internal reliability, construct, convergent and discriminant validity the 32-item DHP-1 conceptual framework is defined for Type 1 & Type 2 Insulin requiring patients. Compliant with FDA guidelines on PRO developments for label claims. Meadows et al 1996; Qual Life Res; 5: ; Goddjin et al. 1996; Qual Life Res; 5: DHP-1 Conceptual framework development

DHP-18 Conceptual framework developed From the original 32-item DHP-1 the 18-item DHP-18 conceptual framework is derived for use with Type 1 and Type 2 diabetes including insulin, oral and diet. Compliant with FDA guidelines on PRO developments for label claims. Meadows et al. Diabetic Med 2000; 17:

More than Current & previous users of the DHP-1/DHP-18

Mean age 63.9 years 91% Type 2 and 9% Type 1 patients completed the questionnaire. Patients (mean) scores on the Disinhibited eating domain by BMI BMI <25 BMI BMI >35 55% 45% Psychological distress MOST AT RISK Comorbidity Severe hypoglycaemia Female > Age Visit to the pyschiatrist ANOVA p=0.05 An example of what the DHP-1/DHP-18 can tell us Source: Boini et al. Health and Quality of Life Outcomes; 2010; 8:124 Psychological distress 3173

2013 New Developments Investigating the minimally important difference of the Diabetes Health Profile (DHP-18) and the EQ-5D and SF-6D in a UK diabetes mellitus po pulation Forthcoming research article For licensing enquiries contact Isis Outcomes Tel: : +44 (0) For further information on the Diabetes Health Profile visit Copyright DHP Research & Consultancy Ltd All rights reserved Diabetes Health Profile (DHP) Licensing Association with Isis Outcomes. Develops eDHP