Volume 74, Pages S55-S59 (December 2008)

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Presentation transcript:

Volume 74, Pages S55-S59 (December 2008) Experimental induction of salt-sensitive hypertension is associated with lymphocyte proliferative response to HSP70 Gustavo Parra, Yasmir Quiroz, Jenny Salazar, Yanauri Bravo, Hector Pons, Maribel Chavez, Richard J. Johnson, Bernardo Rodriguez- Iturbe Kidney International Volume 74, Pages S55-S59 (December 2008) DOI: 10.1038/ki.2008.513 Copyright © 2008 International Society of Nephrology Terms and Conditions

Figure 1 Renal expression of HSP70. (a) Renal expression of HSP70 determined by image analysis in the experimental model of nitric oxide synthase inhibition (L-NAME), protein overload (PO) proteinuria, and short-term angiotensin II infusion (Ang II). Data indicate mean±s.e. ***P<0.001 and *P<0.05. Photomicrographs show the typical distribution of HSP70 in the renal section of a rat from the PO group (b) and from a control rat receiving intraperitoneal saline solution (c). Kidney International 2008 74, S55-S59DOI: (10.1038/ki.2008.513) Copyright © 2008 International Society of Nephrology Terms and Conditions

Figure 2 Proliferation index of T lymphocytes. Proliferation index of T lymphocytes harvested from the spleen of rats of the nitric oxide synthase inhibition (L-NAME), protein overload (PO), and short-term angiotensin II infusions (Ang II groups) shown in black columns, and the corresponding controls (shown in open columns) cultured with HSP70. Data indicate mean±s.e. *P<0.05 and **P<0.01. Kidney International 2008 74, S55-S59DOI: (10.1038/ki.2008.513) Copyright © 2008 International Society of Nephrology Terms and Conditions