Lipid Profiles in Out-of-Hospital Sudden Unexpected Death

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Lipid Profiles in Out-of-Hospital Sudden Unexpected Death Nisha Hosadurg, MD, Brittany M. Bogle, PhD, MPH, Golsa Joodi, MD, Murrium I. Sadaf, MD, Irion Pursell, RN, Philip M. Mendys, PharmD, John P. Mounsey, MD, PhD, Ross J. Simpson, MD, PhD Mayo Clinic Proceedings: Innovations, Quality & Outcomes Volume 2, Issue 3, Pages 257-266 (September 2018) DOI: 10.1016/j.mayocpiqo.2018.06.010 Copyright © 2018 Mayo Foundation for Medical Education and Research Terms and Conditions

Figure 1 Ascertainment of OHSUD cases. DNR = do not resuscitate; EMS = emergency medical services; HDL-C = high-density lipoprotein cholesterol; LDL-C = low-density lipoprotein cholesterol; OHSUD = out-of-hospital sudden unexpected death; TC = total cholesterol; TG = triglyceride. Mayo Clinic Proceedings: Innovations, Quality & Outcomes 2018 2, 257-266DOI: (10.1016/j.mayocpiqo.2018.06.010) Copyright © 2018 Mayo Foundation for Medical Education and Research Terms and Conditions

Figure 2 Odds ratios (95% CIs) of out-of-hospital sudden unexpected death associated with various lipid measures, using local controls as the reference group. Odds ratios (95% CIs) depicted are obtained from model 3, which is adjusted for age, sex, body mass index, diabetes mellitus, and interaction between respective lipid measure and lipid-lowering medication use. For the TG/HDL-C ratio, model 3 adjusts for age, sex, body mass index, and diabetes mellitus. For the LDL-C level and LDL-C/HDL-C ratio, model 3 additionally adjusts for TG level (as continuous variable). HDL-C = high-density lipoprotein cholesterol; LDL-C = low-density lipoprotein cholesterol; OR = odds ratio; TC = total cholesterol; TG = triglyceride. Mayo Clinic Proceedings: Innovations, Quality & Outcomes 2018 2, 257-266DOI: (10.1016/j.mayocpiqo.2018.06.010) Copyright © 2018 Mayo Foundation for Medical Education and Research Terms and Conditions