PROGRAMMABLE MEDICATION INFUSION PUMP Non-Confidential Overview January 2016 Non-Confidential Overview

Executive Summary Globally patented programmable, sterilizable cost effective single use medication infusion pump with established multi-year clinical use (approximately 500,000 uses) Pump includes numerous safety design features with both mechanical and electronic redundancy Product range from programmable to re-programmable versions and next generation concepts which could be multi-use Intellectual property includes 5 patent families including 8 US issued patents, 3 issued international patents and a pending European application as well as know-how and trade secrets

Market Opportunities Single use programmable and re-programmable medication delivery system for applications such as regional pain management for in-patient care Programmable medication delivery system for home care use by patients outside of supervised health care settings Sterilizable design and integrated system with redundant safety features and accurate flow rates for medication delivery per labeling and cleared indications

Key Advantages/Patented Features Medication delivery system is sterilizable by fluids/gases through its patented integrated design Does not require additional assembly Prevents inadvertent delivery of medication Detects blockage in the delivery system Empty detection feature Can be tested with a testing instrument Carrying strap built into the device Two labels provide utility for caregivers and patients Pump will not re-set programming when batteries are changed Can be re-programmed

Patent Listing

Integrated Medication Delivery System US 6,679,862 Priority date is 2001 1. An integrated medication delivery system for delivering medication to a patient herein said system is suitable for complete sterilization by a sterilization fluid, said system comprising: a base housing; a medication reservoir disposed about said base housing for storing the medication to be deliver to the patient; a pump assembly supported by said base housing for delivering the medication to the patient, said pump assembly comprising a pump housing having a pump inlet and a pump outlet, wherein said pump inlet and said pump outlet alternate between an open and a closed state to deliver the medication to the patient; a port extending from said base housing, said port being in fluid communication with said medication reservoir and said pump assembly during sterilization to provide access for the sterilization fluid to flow into said medication reservoir and said pump assembly; an actuator disposed in said base housing and operatively engaging said pump inlet and said pump outlet to retain both said pump inlet and said pump outlet in said open state during sterilization such that the sterilization fluid can penetrate into said medication reservoir, said pump inlet, said pump housing, and said pump outlet to completely sterilize said system; and a first pinch lever disposed at said pump inlet that is normally-biased to maintain said pump inlet in said closed state, and a second pinch lever disposed at said pump outlet that is normally-biased to maintain said pump outlet in said closed state. Representative Claim

Reprogrammable fluid delivery system US 8,147,451 Priority date is 2005 1. A system for delivering fluid to a patient, comprising: a reservoir for storing the fluid to be delivered to the patient; a fluid discharge device operatively coupled to said reservoir for delivering the fluid from said reservoir to the patient; a controller that operates said fluid discharge device; an input device in electronic communication with said controller to set at least one operating parameter of said system wherein said controller operates said fluid discharge device based on said at least one operating parameter and locks said system after said at least one operating parameter is set such that said at least one operating parameter is unable to be modified; and a display in electronic communication with said controller that displays a plurality of alphanumeric characters and a code defined by a predetermined pattern of said alphanumeric characters wherein said code changes at least once during use of said system, said controller unlocking said system upon receiving said code thereby allowing a user to reset said at least one operating parameter Representative Claim

Intellectual Property Purchasing Opportunity Overview Exclusive world-wide utility and design patents covering this novel medication delivery infusion pump Assignment of know-how related to future concepts that were not yet commercialized Trade secrets related to manufacturing methods and programming processes

Other Assets Design control files, technical reports Engineering drawings for pumps and test equipment Injection molding tooling Software source code

Process/Contacts Access to full presentation and data room after signed NDA Stryker contact: