Emerging Regimens in Relapsed/Refractory Indolent Non-Hodgkin Lymphoma

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Presentation transcript:

Emerging Regimens in Relapsed/Refractory Indolent Non-Hodgkin Lymphoma

Introduction

The Current Treatment Algorithm for FL

The Current Treatment Algorithm for MZL

Treatment Options for MCL

Treatment Options for R/R WM

What Is the Goal of Therapy in iNHL?

AUGMENT: Study Design

AUGMENT: Patient Characteristics

PFS in the ITT Population by IRC

OS in Patients With FL (Prespecified Subgroup Analysis)

Safety Profile in the AUGMENT Trial: AEs of Interest

CHRONOS-1: Methods

CHRONOS-1 Results

CHRONOS-1: Response Evaluation by Independent Assessment

INNOVATETM: Study Schema

INNOVATETM: Efficacy Results

SAKK 35/03 Trial Design

SAKK 35/03 Efficacy Results

Complement A+B: Ofatumumab + Bendamustine vs Bendamustine Alone

CONTRALTO Trial: Baseline Characteristics

CONTRALTO Trial: Safety

CONTRALTO Trial: Best Overall Response

Acalabrutinib Monotherapy in R/R MCL

Acalabrutinib: Efficacy Results

Acalabrutinib: Safety Findings

Lenalidomide Following Autologous Transplantation: MCL 0208 Trial

MCL 0208 Trial: Efficacy Results

The Potential Relevance of the Recent Data on Current Practice in FL

The Concept of "Chemotherapy-Free" Strategies

The Impact of New Data on the MCL Paradigm

Conclusions

Abbreviations

Abbreviations (cont)

Abbreviations (cont)

Abbreviations (cont)