© Scott Harris University of Southampton Analysing Continuous Data Practical Questions Analysing Continuous Data Please use the dd month yyyy format for the date for example 11 January 2008. The main title can be one or two lines long. Analysing Coninuous data

© Scott Harris University of Southampton Practical Questions From the course webpage download the file HbA1c.sav by clicking the right mouse button on the file name and selecting Save Target As. The dataset is pre-labelled and contains data on Blood sugar reduction for 245 patients divided into 3 groups. Produce Histograms for the reduction in blood sugar (HBA1CRED), both combined across the three treatment groups and split separately by treatment group. Do you think that the data follow a normal distribution? Analysing Coninuous data

© Scott Harris University of Southampton Practical Questions Assuming that the outcome variable is normally distributed conduct a suitable statistical test to compare the starting HbA1c level (HBA1C_1) against a value of 7 (the level below which good control of glucose levels is accepted). What are the key statistics that should be reported and what are your conclusions from this test? Assuming that the outcome variable is NOT normally distributed conduct a suitable statistical test to compare the starting HbA1c level (HBA1C_1) against a value of 7. What are the key statistics that should be reported and what are your conclusions from this test? Analysing Coninuous data

© Scott Harris University of Southampton Practical Questions Assuming that the outcome variable is normally distributed: Conduct a suitable statistical test to compare the reduction in HbA1c level (HBA1C_1 & HBA1C_2) across the entire cohort. What are the key statistics that should be reported and what are your conclusions from this test? Conduct a suitable statistical test to look directly at the reduction in HbA1c level (HBA1CRED). Does this test agree with the one from part i? Assuming that the outcome variable is NOT normally distributed: Analysing Coninuous data

© Scott Harris University of Southampton Practical Questions Assuming that the outcome variable is normally distributed: Conduct a suitable statistical test to compare the finishing HbA1c level (HBA1C_2) between groups 1 and 2. What are the key statistics that should be reported and what are your conclusions from this test? Repeat the analysis from part i, but this time comparing groups 1 and 3. What are your conclusions from this test? Assuming that the outcome variable is NOT normally distributed: Analysing Coninuous data