Twenty-Year Single-Center Experience With the Medtronic Open Pivot Mechanical Heart Valve Guido J. Van Nooten, MD, PhD, Thierry Bové, MD, Yves Van Belleghem,

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Twenty-Year Single-Center Experience With the Medtronic Open Pivot Mechanical Heart Valve Guido J. Van Nooten, MD, PhD, Thierry Bové, MD, Yves Van Belleghem, MD, Katrien François, MD, PhD, Frank Caes, MD, Guy Vandenplas, MD, Michel De Pauw, MD, Yves Taeymans, MD, PhD The Annals of Thoracic Surgery Volume 97, Issue 4, Pages 1306-1313 (April 2014) DOI: 10.1016/j.athoracsur.2013.11.035 Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Distribution of all mechanical valves of each size in each position and by decade. (A) Open Pivot mechanical heart valve size in each anatomic position. (B) Age distribution. The Annals of Thoracic Surgery 2014 97, 1306-1313DOI: (10.1016/j.athoracsur.2013.11.035) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Patient survival. (♦ = aorta; □ = mitral.) The Annals of Thoracic Surgery 2014 97, 1306-1313DOI: (10.1016/j.athoracsur.2013.11.035) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Freedom from thromboembolism. (♦ = aorta; □ = mitral.) The Annals of Thoracic Surgery 2014 97, 1306-1313DOI: (10.1016/j.athoracsur.2013.11.035) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Freedom from bleeding. (♦ = aorta; ▪ = mitral.) The Annals of Thoracic Surgery 2014 97, 1306-1313DOI: (10.1016/j.athoracsur.2013.11.035) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 Composite thrombosis, thromboembolism, and bleeding odds at increasing international normalized ratio (INR) 0.5 values in aortic valve patients. (OR = odds ratio; (♦ = thrombosis; ● = thromboembolism; ▲ = bleeding; × = adverse events.) The Annals of Thoracic Surgery 2014 97, 1306-1313DOI: (10.1016/j.athoracsur.2013.11.035) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 6 Composite thrombosis, thromboembolism, and bleeding odds at increasing international normalized ratio (INR) 0.5 values in mitral valve patients. (OR = odds ratio; (♦ = thrombosis; ▪ = thromboembolism; ▲ = bleeding; × = adverse events.) The Annals of Thoracic Surgery 2014 97, 1306-1313DOI: (10.1016/j.athoracsur.2013.11.035) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions