Doppler study of middle cerebral artery blood flow velocity and cerebral autoregulation during a simulated ascent of Mount Everest Aram Ter Minassian,

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Presentation transcript:

Doppler study of middle cerebral artery blood flow velocity and cerebral autoregulation during a simulated ascent of Mount Everest Aram Ter Minassian, MD, Laurent Beydon, MD, Mauro Ursino, PhD, Bernard Gardette, PhD, Claude Gortan, PhD, Jean Paul Richalet, MD, PhD Wilderness & Environmental Medicine Volume 12, Issue 3, Pages 175-183 (September 2001) DOI: 10.1580/1080-6032(2001)012[0175:DSOMCA]2.0.CO;2 Copyright © 2001 Wilderness Medical Society Terms and Conditions

Figure 1 Spectral outline of continuous transcranial Doppler for middle cerebral artery blood flow velocity (MCAv): examples of 2 typical patterns recorded at 8000m. Upper panel: continuous MCAv oscillations with a periodicity of 20 to 30 seconds. Lower panel: absence of MCAv oscillations. The sharp decreases in MCAv correspond to transient common carotid compression. Note that during MCAv oscillations, transient hyperemic responses were calculated only for the compression test, which was performed at the zenith of an MCAv wave. Wilderness & Environmental Medicine 2001 12, 175-183DOI: (10.1580/1080-6032(2001)012[0175:DSOMCA]2.0.CO;2) Copyright © 2001 Wilderness Medical Society Terms and Conditions

Figure 2 Transient hyperemic response (THR) of middle cerebral artery blood flow velocity (MCAv) at sea level after common carotid artery release (upper panel). Same subject at 8000m. Note the absence of THR. Mean MCAv is increased and amplitude of undulation is decreased. Wilderness & Environmental Medicine 2001 12, 175-183DOI: (10.1580/1080-6032(2001)012[0175:DSOMCA]2.0.CO;2) Copyright © 2001 Wilderness Medical Society Terms and Conditions