Volume 152, Issue 1, Pages (January 2019)

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Volume 152, Issue 1, Pages 127-132 (January 2019) The cost-effectiveness of opportunistic salpingectomy versus standard tubal ligation at the time of cesarean delivery for ovarian cancer risk reduction  Akila Subramaniam, Brett D. Einerson, Christina T. Blanchard, Britt K. Erickson, Jeff Szychowski, Charles A. Leath, Joseph R. Biggio, Warner K. Huh  Gynecologic Oncology  Volume 152, Issue 1, Pages 127-132 (January 2019) DOI: 10.1016/j.ygyno.2018.11.009 Copyright © 2018 Elsevier Inc. Terms and Conditions

Fig. 1 Two-way sensitivity analysis of ovarian cancer risk reduction estimates for salpingectomy and bilateral tubal ligation. Legend: Blue line signifies the threshold of cost-effectiveness at a willingness-to-pay of $100,000 per QALY. Combinations of input variables below and to the right of the blue line denote circumstances in which salpingectomy is not cost-effective. Green line signifies the threshold of cost-savings. Combinations of input variables above and to the left of the green line denote circumstances in which salpingectomy is cost-saving. Between the blue and green line, salpingectomy is cost-effective. Gynecologic Oncology 2019 152, 127-132DOI: (10.1016/j.ygyno.2018.11.009) Copyright © 2018 Elsevier Inc. Terms and Conditions

Fig. 2 Results of the probabilistic sensitivity analysis. Legend: Each blue dot is plotted as the result of a single simulation among 10,000 simulations in probabilistic sensitivity analysis. The black dashed diagonal line is the threshold for cost-effectiveness at a willingness-to-pay of $100,000 per QALY. Dots below and to the right of the diagonal line signify simulations in which salpingectomy was cost-effective. The solid black line forming a circle is the 95% confidence ellipse in which 95% of simulations are expected to result. Gynecologic Oncology 2019 152, 127-132DOI: (10.1016/j.ygyno.2018.11.009) Copyright © 2018 Elsevier Inc. Terms and Conditions