Building a Metal Binding Domain, One Half at a Time

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Presentation transcript:

Building a Metal Binding Domain, One Half at a Time Sarah L.J Michel, Jeremy M Berg Chemistry & Biology Volume 9, Issue 6, Pages 667-668 (June 2002) DOI: 10.1016/S1074-5521(02)00160-6

Figure 1 Alternative Zinc Binding Modes In the TAZ domain structure, the Cys-C4-Cys loop and the His-X4-Cys helix bind to different metal ions. In the CHANCE domain fold, these two substructures come together to form a novel zinc-binding module. Chemistry & Biology 2002 9, 667-668DOI: (10.1016/S1074-5521(02)00160-6)