Asthma treatment and asthma prevention: A tale of 2 parallel pathways

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Presentation transcript:

Asthma treatment and asthma prevention: A tale of 2 parallel pathways Fernando D. Martinez, MD Journal of Allergy and Clinical Immunology Volume 119, Issue 1, Pages 30-33 (January 2007) DOI: 10.1016/j.jaci.2006.10.020 Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Hypothetical representation of 2 separate developmental pathways present in persistent asthma, one sensitive (left side) and the other insensitive (right side) to ICSs. These pathways would determine ongoing symptom-related inflammation and deficits in lung function growth and potentially “airway remodeling,” respectively. Both pathways can influence the measured level of BHR during childhood. COPD, Chronic obstructive pulmonary disease. Journal of Allergy and Clinical Immunology 2007 119, 30-33DOI: (10.1016/j.jaci.2006.10.020) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions