Volume 61, Issue 3, Pages (March 2002)

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Volume 61, Issue 3, Pages 1143-1152 (March 2002) Association between interleukin-6 and carotid atherosclerosis in hemodialysis patients Akihiko Kato, Mari Odamaki, Takako Takita, Yukitaka Maruyama, Hiromichi Kumagai, Akira Hishida Kidney International Volume 61, Issue 3, Pages 1143-1152 (March 2002) DOI: 10.1046/j.1523-1755.2002.00215.x Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 1 Relationship between log interleukin-6 (IL-6) and serum albumin (A) and creatinine (B). Serum log IL-6 levels were significantly and inversely correlated with serum albumin (r = -0.328, P < 0.01) or creatinine (r = -0.297, P < 0.01). Kidney International 2002 61, 1143-1152DOI: (10.1046/j.1523-1755.2002.00215.x) Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 2 Relationship between age and carotid intima-media thickness (IMT) or carotid cross-sectional intima-media area (IMarea). A significant linear relationship was found between patient's age and IMT (r = 0.453, P < 0.01) or IMarea (r = 0.504, P < 0.01). Kidney International 2002 61, 1143-1152DOI: (10.1046/j.1523-1755.2002.00215.x) Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 3 Association between circulating log IL-6 and carotid intima-media thickness (IMT) or carotid cross-sectional intima-media area (IMarea) in dialysis patients. There was a significant positive relationship between log IL-6 and IMT (r = 0.278, P < 0.01) or IMarea (r = 0.344, P < 0.01). Kidney International 2002 61, 1143-1152DOI: (10.1046/j.1523-1755.2002.00215.x) Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 4 Relationship between serum IgA antibody titer for Chlamydia pneumoniae and maximal diameter of carotid plaque. There was a significant and linear association between IgA antibodies and maximal plaque diameter by sonography (r = 0.293, P < 0.04). The dotted line denotes the cut-off value. Kidney International 2002 61, 1143-1152DOI: (10.1046/j.1523-1755.2002.00215.x) Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 5 A positive relationship between serum log IL-6 and IgG, or IgA titers of Chlamydia pneumoniae. A significant positive relationship was existed between log IL-6 and IgG antibodies (r = 0.277, P < 0.01) or IgA antibodies (r = 0.192, P < 0.02) to Chlamydia pneumoniae. Kidney International 2002 61, 1143-1152DOI: (10.1046/j.1523-1755.2002.00215.x) Copyright © 2002 International Society of Nephrology Terms and Conditions