Efficacy of thoracic endovascular stent repair for chronic type B aortic dissection with aneurysmal degeneration  Salvatore T. Scali, MD, Robert J. Feezor,

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Presentation transcript:

Efficacy of thoracic endovascular stent repair for chronic type B aortic dissection with aneurysmal degeneration  Salvatore T. Scali, MD, Robert J. Feezor, MD, Catherine K. Chang, MD, David H. Stone, MD, Philip J. Hess, MD, Tomas D. Martin, MD, Thomas S. Huber, MD, PhD, Adam W. Beck, MD  Journal of Vascular Surgery  Volume 58, Issue 1, Pages 10-17.e1 (July 2013) DOI: 10.1016/j.jvs.2012.12.071 Copyright © 2013 Society for Vascular Surgery Terms and Conditions

Fig 1 This figure demonstrates the relative change in maximal descending thoracic aortic diameter after thoracic endovascular aortic aneurysm repair (TEVAR) for chronic type B aortic dissection (cTBAD) with aneurysm. The differential impact of partial vs complete thrombosis of the false lumen (FL) led to significant differences (P = .02) in average diameter reduction after endograft repair. Journal of Vascular Surgery 2013 58, 10-17.e1DOI: (10.1016/j.jvs.2012.12.071) Copyright © 2013 Society for Vascular Surgery Terms and Conditions

Fig 2 This demonstrates a comparison of the average maximal thoracic aortic diameter change after thoracic endovascular aortic aneurysm repair (TEVAR) for chronic type B aortic dissection (cTBAD) with aneurysm formation as a function of residual false lumen (FL) patency. Patients with isolated infrarenal FL patency vs visceral aortic segmental patency vs distal descending thoracic aortic FL patency are compared. A significant difference (P < .0005) in diameter outcome is noted and primarily impacted by persistent perfusion of the FL in the distal descending thoracic aorta resulting in progression of aneurysm size. Journal of Vascular Surgery 2013 58, 10-17.e1DOI: (10.1016/j.jvs.2012.12.071) Copyright © 2013 Society for Vascular Surgery Terms and Conditions

Fig 3 Kaplan-Meier curve with 95% confidence intervals (CIs) of secondary intervention after thoracic endovascular aortic aneurysm repair (TEVAR) for chronic type B aortic dissection (cTBAD) with aneurysm. All displayed intervals have ≤10% standard error of the mean. Journal of Vascular Surgery 2013 58, 10-17.e1DOI: (10.1016/j.jvs.2012.12.071) Copyright © 2013 Society for Vascular Surgery Terms and Conditions

Fig 4 Life table estimate of long-term survival with 95% confidence intervals (CIs) after thoracic endovascular aortic aneurysm repair (TEVAR) for chronic type B aortic dissection (cTBAD) for aneurysm. All displayed intervals have ≤10% standard error of the mean. Journal of Vascular Surgery 2013 58, 10-17.e1DOI: (10.1016/j.jvs.2012.12.071) Copyright © 2013 Society for Vascular Surgery Terms and Conditions

Fig 5 This figure compares the proportion of patients surviving between cohorts requiring reintervention and those who did not. No statistically significant difference was noted between the two subgroups (log-rank, P = .48). All displayed intervals have ≤10% standard error of the mean. Journal of Vascular Surgery 2013 58, 10-17.e1DOI: (10.1016/j.jvs.2012.12.071) Copyright © 2013 Society for Vascular Surgery Terms and Conditions

Fig 6 Kaplan-Meier estimates of survival dichotomized by presence or absence of favorable aortic remodeling. Favorable aortic remodeling was defined as a ≥5 mm decrease in maximal descending thoracic aortic diameter and no need for aortic reintervention either at the intended treatment zone or remote aortic sites. No difference in estimated long-term survival is present between the two groups (log-rank, P = .18). All displayed intervals have ≤10% standard error of the mean. Journal of Vascular Surgery 2013 58, 10-17.e1DOI: (10.1016/j.jvs.2012.12.071) Copyright © 2013 Society for Vascular Surgery Terms and Conditions

Supplementary Fig (online only) Study selection criteria algorithm. cTBAD, Chronic type B aortic dissection; TEVAR, thoracic endovascular aortic aneurysm repair. Journal of Vascular Surgery 2013 58, 10-17.e1DOI: (10.1016/j.jvs.2012.12.071) Copyright © 2013 Society for Vascular Surgery Terms and Conditions