Effects of folic acid and zinc sulfate on male factor subfertility: a double-blind, randomized, placebo-controlled trial Wai Yee Wong, M.D, Ph.D., Hans.

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Presentation transcript:

Effects of folic acid and zinc sulfate on male factor subfertility: a double-blind, randomized, placebo-controlled trial Wai Yee Wong, M.D, Ph.D., Hans M.W.M Merkus, M.D., Ph.D., Chris M.G Thomas, Ph.D., Roelof Menkveld, Ph.D., Gerhard A Zielhuis, Ph.D., Régine P.M Steegers-Theunissen, M.D., Ph.D. Fertility and Sterility Volume 77, Issue 3, Pages 491-498 (March 2002) DOI: 10.1016/S0015-0282(01)03229-0

Figure 1 Trial profile. Wong. Folate, zinc, and male subfertility. Fertil Steril 2002. Fertility and Sterility 2002 77, 491-498DOI: (10.1016/S0015-0282(01)03229-0)

Figure 2 Median preintervention and postintervention sperm concentrations in subfertile (A) and fertile (B) men. ∗P<.001 for comparison between baseline and posttreatment values. ■ pre-intervention; □ postintervention. Wong. Folate, zinc, and male subfertility. Fertil Steril 2002. Fertility and Sterility 2002 77, 491-498DOI: (10.1016/S0015-0282(01)03229-0)