Ultrasound in the diagnosis of calcium pyrophosphate dihydrate deposition disease. A systematic literature review and a meta-analysis G. Filippou, A.

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Presentation transcript:

Ultrasound in the diagnosis of calcium pyrophosphate dihydrate deposition disease. A systematic literature review and a meta-analysis G. Filippou, A. Adinolfi, A. Iagnocco, E. Filippucci, M.A. Cimmino, I. Bertoldi, V. Di Sabatino, V. Picerno, A. Delle Sedie, L.M. Sconfienza, B. Frediani, C.A. Scirè Osteoarthritis and Cartilage Volume 24, Issue 6, Pages 973-981 (June 2016) DOI: 10.1016/j.joca.2016.01.136 Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Phases of the study selection (PRISMA flow-chart). Osteoarthritis and Cartilage 2016 24, 973-981DOI: (10.1016/j.joca.2016.01.136) Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 ROC curves about the sensitivity and specificity values relating any structures or a single one. Osteoarthritis and Cartilage 2016 24, 973-981DOI: (10.1016/j.joca.2016.01.136) Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Evaluation of the methodological quality of the included studies. Osteoarthritis and Cartilage 2016 24, 973-981DOI: (10.1016/j.joca.2016.01.136) Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

Fig. 4 Characteristic US images of CPPD appearance. Even if these patterns are frequently observed, they are not exclusive of the appearance of CPPD and other forms and shapes of deposits may be encountered. CPPD appears as hyperechoic deposits with echogenicity similar to that of the bone profile. A: hyperechoic deposits within the hyaline cartilage layer of the knee B: hyperechoic deposits within Achilles tendon. C: hyperechoic deposits within synovial fluid (only two of them indicated in this illustration). D: hyperechoic deposits within meniscal fibrocartilage. Legend: arrowheads: CPP deposition, curved arrows: the bone profile, arrows: tendon margins, HC: hyaline cartilage layer (anechoic/hypoechoic on US), SF (anechoic/hypoechoic on US), grey line in frame D individuates the lateral meniscus of the knee. Osteoarthritis and Cartilage 2016 24, 973-981DOI: (10.1016/j.joca.2016.01.136) Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

Osteoarthritis and Cartilage 2016 24, 973-981DOI: (10. 1016/j. joca Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

Osteoarthritis and Cartilage 2016 24, 973-981DOI: (10. 1016/j. joca Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions