Successful Prevention of Acute Graft-versus-Host Disease Using Low-Dose Antithymocyte Globulin after Mismatched, Unrelated, Hematopoietic Stem Cell Transplantation.

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Successful Prevention of Acute Graft-versus-Host Disease Using Low-Dose Antithymocyte Globulin after Mismatched, Unrelated, Hematopoietic Stem Cell Transplantation for Acute Myelogenous Leukemia Hee-Je Kim, Woo-Sung Min, Byung-Sik Cho, Ki-Seong Eom, Yoo-Jin Kim, Chang-Ki Min, Seok Lee, Seok-Goo Cho, Jong-Youl Jin, Jong-Wook Lee, Chun-Choo Kim Biology of Blood and Marrow Transplantation Volume 15, Issue 6, Pages 704-717 (June 2009) DOI: 10.1016/j.bbmt.2009.02.010 Copyright © 2009 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Comparison of the estimated 6-year OS and EFS after allogeneic hematopoietic stem cell transplantation from multinational unrelated donors, n = 103. Biology of Blood and Marrow Transplantation 2009 15, 704-717DOI: (10.1016/j.bbmt.2009.02.010) Copyright © 2009 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Comparison of the (A) OS and (B) EFS rates after selecting donors with HLA-matches (group 1, n = 54; continuous line) and -mismatches (group 2, n = 49; dashed line) after allogeneic hematopoietic stem cell transplantation from multinational unrelated donors. Biology of Blood and Marrow Transplantation 2009 15, 704-717DOI: (10.1016/j.bbmt.2009.02.010) Copyright © 2009 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 3 Comparison of the (A) OS and (B) EFS rates between group 3 (with ATG, n = 24; continuous line) and group 4 (without ATG, n = 25; dashed line), according to the use of ATG or not for patients who received uHSCT from HLA-mismatched donors. Biology of Blood and Marrow Transplantation 2009 15, 704-717DOI: (10.1016/j.bbmt.2009.02.010) Copyright © 2009 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 4 The overall estimated CIR rate after allogeneic hematopoietic stem cell transplantation from multinational unrelated donors, n = 48 (A), and there was no definite difference of CIR between groups 3 and 4 (B). Biology of Blood and Marrow Transplantation 2009 15, 704-717DOI: (10.1016/j.bbmt.2009.02.010) Copyright © 2009 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 5 The overall estimated cumulative incidence of aGVHD and cGVHDs after allogeneic hematopoietic stem cell transplantation from multinational unrelated donors, n = 48: (A) aGVHD, (B) cGVHD. Biology of Blood and Marrow Transplantation 2009 15, 704-717DOI: (10.1016/j.bbmt.2009.02.010) Copyright © 2009 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 6 The overall estimated nonrelapse TRM rate after allogeneic hematopoietic stem cell transplantation from multinational unrelated donors, n = 48 (A), but there was a statistically significant difference between groups 3 and 4 (B). Biology of Blood and Marrow Transplantation 2009 15, 704-717DOI: (10.1016/j.bbmt.2009.02.010) Copyright © 2009 American Society for Blood and Marrow Transplantation Terms and Conditions