Relating Autoimmune Cytopenias after Hematopoietic Cell Transplantation (HCT) to Transplant-Variables and Immune Reconstitution: A Predictor Analysis

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Presentation transcript:

Relating Autoimmune Cytopenias after Hematopoietic Cell Transplantation (HCT) to Transplant-Variables and Immune Reconstitution: A Predictor Analysis Celina L. Szanto, Jurgen Langenhorst, Charlotte van Kesteren, Coco de Koning, Stefan Nierkens, Caroline A. Lindemans, Jaap-Jan Boelens Biology of Blood and Marrow Transplantation Volume 24, Issue 3, Pages S183-S184 (March 2018) DOI: 10.1016/j.bbmt.2017.12.135 Copyright © 2017 Terms and Conditions

Figure 1 Cytopenia free survival (CFS) shows that patients with aGVHD grade 2-4 have a significant higher change (P = .00046) to develop AIC. Biology of Blood and Marrow Transplantation 2018 24, S183-S184DOI: (10.1016/j.bbmt.2017.12.135) Copyright © 2017 Terms and Conditions

Figure 2 Immunoglobulin profiles show increased levels of IgM, IgG and IgA prior to AIC development. Biology of Blood and Marrow Transplantation 2018 24, S183-S184DOI: (10.1016/j.bbmt.2017.12.135) Copyright © 2017 Terms and Conditions

Figure 3 B-cell reconstitution after HCT stratified in CB (n = 193) and BM (n = 157) transplanted patients. Biology of Blood and Marrow Transplantation 2018 24, S183-S184DOI: (10.1016/j.bbmt.2017.12.135) Copyright © 2017 Terms and Conditions