Trispecific Killer Engager CD16xIL15xCD33 Enhances Alloreactivity of NK Cells Against Aberrant Mast Cells of Patients with Systemic Mastocytosis Hyun.

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Presentation transcript:

Trispecific Killer Engager CD16xIL15xCD33 Enhances Alloreactivity of NK Cells Against Aberrant Mast Cells of Patients with Systemic Mastocytosis Hyun Don Yun, Martin Felices, Daniel A. Vallera, Sarah Cooley, Jason R. Gotlib, Celalettin Ustun, Jeffrey S. Miller Biology of Blood and Marrow Transplantation Volume 24, Issue 3, Pages S174-S175 (March 2018) DOI: 10.1016/j.bbmt.2017.12.109 Copyright © 2017 Terms and Conditions

Figure 1 Functional assay of NK cells by 4-hour incubation with BM samples of SM patients. ****: P < .001. Biology of Blood and Marrow Transplantation 2018 24, S174-S175DOI: (10.1016/j.bbmt.2017.12.109) Copyright © 2017 Terms and Conditions

Figure 2 Killing Assay by 4-hour incubation of NK cells with ROSA KIT mast cell line after the target tagged with cell trace. *: P < .05. Biology of Blood and Marrow Transplantation 2018 24, S174-S175DOI: (10.1016/j.bbmt.2017.12.109) Copyright © 2017 Terms and Conditions