T-Cell Large Granular Lymphocytic Leukemia and Pure Red Cell Aplasia in a Patient With Type I Autoimmune Polyendocrinopathy: Response to Immunosuppressive.

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Presentation transcript:

T-Cell Large Granular Lymphocytic Leukemia and Pure Red Cell Aplasia in a Patient With Type I Autoimmune Polyendocrinopathy: Response to Immunosuppressive Therapy MADHAV V. DHODAPKAR, M.D., JOHN A. LUST, M.D., Ph.D., ROBERT L. PHYLIKY, M.D. Mayo Clinic Proceedings Volume 69, Issue 11, Pages 1085-1088 (November 1994) DOI: 10.1016/S0025-6196(12)61377-9 Copyright © 1994 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 1 Southern blot analysis for detection of T-cell receptor gene rearrangement with use of probe for J β2 region after EcoRI digestion. Lane 1 is normal control; lanes 2 and 3 are patient samples after and before treatment, respectively. The 4.4-Kb band is germline band, and broken arrows represent clonal rearranged bands. Mayo Clinic Proceedings 1994 69, 1085-1088DOI: (10.1016/S0025-6196(12)61377-9) Copyright © 1994 Mayo Foundation for Medical Education and Research Terms and Conditions