Comparative genomics and DNA array-based genotyping of pandemic Staphylococcus aureus strains encoding Panton-Valentine leukocidin S. Monecke, B. Berger-Bächi,

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Presentation transcript:

Comparative genomics and DNA array-based genotyping of pandemic Staphylococcus aureus strains encoding Panton-Valentine leukocidin S. Monecke, B. Berger-Bächi, G. Coombs, A. Holmes, I. Kay, A. Kearns, H-J. Linde, F. O'Brien, P. Slickers, R. Ehricht Clinical Microbiology and Infection Volume 13, Issue 3, Pages 236-249 (March 2007) DOI: 10.1111/j.1469-0691.2006.01635.x Copyright © 2007 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 1 Antibiotic resistance genes in the strains studied. Panton-Valentine leukocidin (PVL)-positive strains are indicated in bold letters. Black boxes, positive; white boxes, negative; divided boxes, divergent results using the two labelling approaches; shaded boxes, variable. Clinical Microbiology and Infection 2007 13, 236-249DOI: (10.1111/j.1469-0691.2006.01635.x) Copyright © 2007 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 2 Genes for superantigenic toxins in the strains studied. Panton-Valentine leukocidin (PVL)-positive strains are indicated in bold letters. Black boxes, positive; white boxes, negative; divided boxes, divergent results using the two labelling approaches. Clinical Microbiology and Infection 2007 13, 236-249DOI: (10.1111/j.1469-0691.2006.01635.x) Copyright © 2007 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 3 Genes for leukocidins, haemolysins and other virulence factors in the strains studied. Panton-Valentine leukocidin (PVL)-positive strains are indicated in bold letters. Black boxes, positive; white boxes, negative; divided boxes, divergent results using the two labelling approaches; shaded boxes, variable. Clinical Microbiology and Infection 2007 13, 236-249DOI: (10.1111/j.1469-0691.2006.01635.x) Copyright © 2007 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 4 Staphylococcal exotoxin-like (set) genes in the strains studied. Panton-Valentine leukocidin (PVL)-positive strains are indicated in bold letters. Black boxes, positive; white boxes, negative; divided boxes, divergent results using the two labelling approaches; shaded boxes, variable. The set genes are listed in the succession in which they occur in the sequenced strains (for nomenclature and definitions of allelic variants, see Table S2). Clinical Microbiology and Infection 2007 13, 236-249DOI: (10.1111/j.1469-0691.2006.01635.x) Copyright © 2007 European Society of Clinical Infectious Diseases Terms and Conditions