Discriminatory performance (receiver operating characteristics (ROC) analysis) of lung clearance index (LCI) analysed with the different methods. a) ROC.

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Discriminatory performance (receiver operating characteristics (ROC) analysis) of lung clearance index (LCI) analysed with the different methods. a) ROC curves of LCI calculated using the standard analysis (standard), the linear interpolation (linear), the ... Discriminatory performance (receiver operating characteristics (ROC) analysis) of lung clearance index (LCI) analysed with the different methods. a) ROC curves of LCI calculated using the standard analysis (standard), the linear interpolation (linear), the fit-curve method (fit-curve) and the method that uses the first breath below the 2.5% cut-off (1st breath). b) ROC curves of LCI calculated using the end-tidal nitrogen concentration (standard analysis, Cet N2), the mean nitrogen concentration (mean N2) and the median nitrogen concentration (median N2) per breath. AUC: area under the curve. ***: p<0.001, chi-squared test, compared with the standard analysis. Pinelopi Anagnostopoulou et al. ERJ Open Res 2018;4:00021-2017 ©2018 by European Respiratory Society