Study of HIV-2 in monkey Pigtail macaque (Macaca nemestrina) Baboons

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Presentation transcript:

Study of HIV-2 in monkey Pigtail macaque (Macaca nemestrina) Baboons (Papio cynocephalus)

- This species are susceptible to infection with some isolates of HIV-2. - HIV-2 have been developed that induce AIDS-like disease and depletion of CD4+ cell. - Similarities in disease progression and development of AIDS to human HIV infection.

Study of Simian immunodeficiency virus (SIV) in non human primate model -SIV is lentivirus and close related to HIV-1, HIV-2 -It share up to 50% similarity to HIV-1 in nucleotid level and share about 88% of amino acid homology to HIV-2