97. Gene Transfer Using a Snake Venom Derived Vascular Endothelial Growth Factor Induces Robust Angiogenesis and Improves Ventricular Function in Ischemic.

Slides:

Advertisements

Similar presentations

Date of download: 7/3/2016 Copyright © The American College of Cardiology. All rights reserved. From: Cotransfection of Vascular Endothelial Growth Factor-A.

Advertisements

Volume 172, Issue 3, Pages (September 2004)

Phase I Study of H5.020CMV.PDGF-β to Treat Venous Leg Ulcer Disease

Ultraviolet B-Induced Skin Angiogenesis Is Associated with a Switch in the Balance of Vascular Endothelial Growth Factor and Thrombospondin-1 Expression

Volume 20, Issue 2, (February 2012)

414. A Novel Clinical Severity Scoring Measure in Canine X-Linked Myotubular Myopathy: Results Following Systemic AAV Gene Replacement Molecular Therapy

209. Use of Helicobacter pyroli Neutrophil Activating Protein (NAP) as an Immune- Modulatory Agent To Enhance the Efficacy of Oncolytic Adenovirus Therapy.

446. Gender Differences in the Osteogenic & Chondrogenic Potential of Human Muscle- Derived Stem Cells In Vitro Alex C. Scibetta, Andrea B. Liebowitz,

Genome-editing Technologies for Gene and Cell Therapy

627. Non-Invasive, Multimodal Imaging of Microvesicles with Metabolically Biotinylated, Membrane-Bound Gaussia Luciferase Molecular Therapy Volume.

Elizabeth Morris, Alex Scibetta, Aiping Lu, Xueqin Gao, Johnny Huard

162. Stability of Polymer/Plasmid DNA Complexes In Vitro and In Vivo

281. Rapid Generation of Induced Pluripotent Stem Cells (iPSCs) from the Urine of a Patient with Duchenne Muscular Dystrophy Molecular Therapy Volume.

VEGF Gene Delivery to Muscle

Targeted Overexpression of the Angiogenesis Inhibitor Thrombospondin-1 in the Epidermis of Transgenic Mice Prevents Ultraviolet-B-Induced Angiogenesis.

Direct Conversion of Skin Cells into Blood: Alchemy or Science?

Molecular Therapy Volume 20, Pages S261-S262 (May 2012) DOI: /S (16)

Evolving Gene Therapy in Primary Immunodeficiency

Volume 20, Issue 6, Pages (June 2012)

343. Benchtop DNA Synthesizer: Oligo-Templated Polymerization (OTP)

Cellular and molecular mechanism regulating blood flow recovery in acute versus gradual femoral artery occlusion are distinct in the mouse Yagai Yang,

152. The Effects of AdVEGF-B and AdVEGF-D on Angiogenesis and Arteriogenesis in a Novel Porcine Model of Percutaneous Bottleneck Stent Induced Chronic.

637. Effect of PEG Grafting Degree on Morphology and Transfection Efficiency of Polycation-g-PEG/DNA Nanoparticles Molecular Therapy Volume 20, (May.

Phase I Study of H5.020CMV.PDGF-β to Treat Venous Leg Ulcer Disease

John R. Martin, Christopher E. Nelson, Mukesh K

Volume 26, Issue 2, Pages (February 2018)

Expression of angiopoietins 1, 2 and their common receptor tie-2 in relation to the size of endothelial lining gaps and expression of VEGF and VEGF receptors.

Volume 25, Issue 1, Pages 5-7 (January 2017)

Efficacy of fragmin/protamine microparticles containing fibroblast growth factor-2 (F/P MPs/FGF-2) to induce collateral vessels in a rabbit model of hindlimb.

724. Blood-Derived Endothelial Progenitor Cells Can Be Isolated With a Novel Method of Diluted Whole Blood Incubation with AMD3100-Induced Mobilization.

Genome-editing Technologies for Gene and Cell Therapy

Premal Lulla, Carlos A. Ramos Molecular Therapy

Molecular Therapy Volume 20, (May 2012) DOI: /S (16)

Molecular Therapy Volume 7, Issue 5, (May 2003) DOI: /S (16)

Correction Journal of Vascular Surgery

Volume 12, Issue 6, Pages (December 2005)

847. Eradication of Therapy-Resistant Human Prostate Tumors Using an Ultrasound Guided Site-Specific Cancer Terminator Virus Delivery Approach Molecular.

Designer Lipids Advance Systemic siRNA Delivery

Volume 20, Issue 6, Pages (June 2012)

133. Survival with Normal Neurological Development of the Juvenile Lethal Urea Cycle Defect Arginase Deficient Mouse with AAV Gene Therapy Molecular.

660. Bowel/Bladder Sensation and Control in Patients with Spinal Cord Injury Treated with Human Embryonic Stem Cell Therapy Geeta Shroff Molecular Therapy

Carotid plaque instability and ischemic symptoms are linked to immaturity of microvessels within plaques Benjamin J. Dunmore, PhD, Mark J. McCarthy,

68. Site Specific Intra-Placental Gene Transfer Corrects Fetal Growth Restriction in a Novel Mouse Model of Placental Insufficiency (PI) Molecular.

521. Multiplex Genome Editing of TCR°/CD52 Genes as a Platform for “Off the Shelf” Adoptive T-Cell Immunotherapies Molecular Therapy Volume 22, Pages.

Chae-lyul Limg, Yeon-Ju Lee, Sujeong Kim

405. Hindlimb and Forelimb Strength Assessment in a Canine Model of X-Linked Myotubular Myopathy Following AAV-Mediated Gene Replacement Molecular.

674. Molecular, Biochemical and Biomechanical Analysis of Articular Cartilage Repaired with Genetically Modified Chondrocytes Expressing Insulin-Like.

Ultraviolet B-Induced Skin Angiogenesis Is Associated with a Switch in the Balance of Vascular Endothelial Growth Factor and Thrombospondin-1 Expression

287. Improved Outcomes Following Drug-Resistant Immunotherapy in a Human Xenograft Model of Temozolomide-Resistant Glioblastoma Multiforme Harold T.

Molecular Therapy Volume 18, Pages S260-S261 (May 2010) DOI: /S (16)

Jair Bar, MD, PhD, Glenwood D. Goss, MD, FCPSA, FRCPC

318. Targeted Genome Editing of Human Induced Pluripotent Stem Cells Using CRISPR/CAS9 to Generate a Knock-in Type II Collagen Reporter for the Purification.

Volume 19, Issue 4, Pages (April 2011)

In This Issue Molecular Therapy Volume 16, Issue 4, (April 2008)

The VEGF Family, the Inside Story

Thrombospondin-1 Plays a Critical Role in the Induction of Hair Follicle Involution and Vascular Regression During the Catagen Phase Kiichiro Yano, Michael.

372. Targeted Mutagenesis of Ubiquitin-Binding Lysine Residues on the Adeno- Associated Virus (AAV)2 Capsid Improves Its Transduction Efficiency Molecular.

521. AAV Immunotherapy Induces Functional Antigen Specific Regulatory T-Cells to a Neuroantigen: A Potential Treatment for MS Brad E. Hoffman Molecular.

773. Detection of RNA Interference (RNAi) Mediated mRNA Cleavage in Fresh Injected Tumor Tissue from Patients in a Phase I Trial of pbi-shRNA™ Lipoplex.

740. Prevention of Radiation-Induced Lung Injury by Administration of Gene-Modified Mesenchymal Stem Cells Molecular Therapy Volume 20, Pages S285-S286.

Molecular Therapy Volume 21, Pages S247-S248 (May 2013)

Shigeki Yagyu, Malcolm K. Brenner

Volume 71, Issue 9, Pages (May 2007)

86. A Highly Compact Epitope-Based Marker Suicide Gene for Safer and Easier Adoptive T-Cell Gene Therapy Molecular Therapy Volume 20, Pages S35-S36.

297. Minimally Invasive Implantation of Autologous Chondrocytes Transduced with rAAV5-IGF-I Improves Longterm Cartilage Repair in Full-Thickness Chondral.

Apoptosis in CAM vessels after staining with TUNEL

Jingxian Feng, Jiawen Wang, Junsheng Lin, Yong Diao

Shirley Wong, Roderick A. Slavcev

Alex B. Magil, Kathryn Tinckam Kidney International

624. Randomized Phase II Trial of Adjuvant Autologous Tumor Cell Vaccine (FANG™) for High Risk Stage III/IV Ovarian Cancer: Preliminary Results Molecular.

Presentation transcript:

97. Gene Transfer Using a Snake Venom Derived Vascular Endothelial Growth Factor Induces Robust Angiogenesis and Improves Ventricular Function in Ischemic Porcine Myocardium Molecular Therapy Volume 21, (May 2013) DOI: 10.1016/S1525-0016(16)34432-X Copyright © 2013 The American Society of Gene & Cell Therapy Terms and Conditions

Figure 1 Increased vascular permeability is visible in the angiogram as contrast agent leaks out of the vessels (arrowheads) in the gene transfer area. Also pericardial fluid is visible (asterisk). Capillaries are clearly enlarged at the gene transfer area when compared to control group (CD31 stain), and also demonstrate clear pericyte coverage (CD31/aSMA double immunostain). Molecular Therapy 2013 21, DOI: (10.1016/S1525-0016(16)34432-X) Copyright © 2013 The American Society of Gene & Cell Therapy Terms and Conditions