OBP-401-based fluorescence-guided surgery of orthotopic lung cancer.

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OBP-401-based fluorescence-guided surgery of orthotopic lung cancer. OBP-401-based fluorescence-guided surgery of orthotopic lung cancer. (A) Intravital imaging of OBP-401 labelling of A549-RFP lung tumour in situ with GFP. (B) Tumors resected by fluorescence-guided surgery of orthotopic A549-RFP lung cancer labelled with OBP-401 GFP and RFP. Dotted lines show the outline of the tumor border. (C) Representative images after fluorescence-guided surgery. Images were acquired with the OV100 (Olympus). For A, B and C, left panels are low magnification and right panels are high magnification. Shuya Yano et al. BMJ Open Resp Res 2015;2:e000096 ©2015 by British Thoracic Society