Diagnostic accuracy of culture-based and PCR-based detection tests for methicillin- resistant Staphylococcus aureus: a meta-analysis J.M. Luteijn, G.A.A.

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Presentation transcript:

Diagnostic accuracy of culture-based and PCR-based detection tests for methicillin- resistant Staphylococcus aureus: a meta-analysis J.M. Luteijn, G.A.A. Hubben, P. Pechlivanoglou, M.J. Bonten, M.J. Postma Clinical Microbiology and Infection Volume 17, Issue 2, Pages 146-154 (February 2011) DOI: 10.1111/j.1469-0691.2010.03202.x Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 1 Flow chart of the article selection process. Clinical Microbiology and Infection 2011 17, 146-154DOI: (10.1111/j.1469-0691.2010.03202.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 2 Receiver-operating characteristic plot of sensitivity against 1 – specificity for the 15 PCR comparisons included in this meta-analysis. Clinical Microbiology and Infection 2011 17, 146-154DOI: (10.1111/j.1469-0691.2010.03202.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 3 Receiver-operating characteristic plot of sensitivity against 1 – specificity for the 28 18–24 h chromogenic media test comparisons included in this meta-analysis. Clinical Microbiology and Infection 2011 17, 146-154DOI: (10.1111/j.1469-0691.2010.03202.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 4 Receiver-operating characteristic plot of sensitivity against 1 – specificity for the 31 48 h culture (both chromogenic and nonchromogenic) test comparisons included in this meta-analysis. Clinical Microbiology and Infection 2011 17, 146-154DOI: (10.1111/j.1469-0691.2010.03202.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 5 Bivariate summary estimates of sensitivity and specificity for both PCR tests evaluated and the 95% confidence ellipses around these mean values. Clinical Microbiology and Infection 2011 17, 146-154DOI: (10.1111/j.1469-0691.2010.03202.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 6 Bivariate summary estimates of sensitivity and specificity for all five 18–24-h chromogenic media tests evaluated and the 95% confidence ellipses around these mean values. Clinical Microbiology and Infection 2011 17, 146-154DOI: (10.1111/j.1469-0691.2010.03202.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 7 Bivariate summary estimates of sensitivity and specificity for all six 48-h culture (both chromogenic and nonchromogenic) tests evaluated and the 95% confidence ellipses around these mean values. To improve readability, the confidence ellipse of MSA-Cefoxitin 48 h (in light-blue) is not fully covered. Clinical Microbiology and Infection 2011 17, 146-154DOI: (10.1111/j.1469-0691.2010.03202.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions