Estrogen induces glomerulosclerosis in analbuminemic rats

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Estrogen induces glomerulosclerosis in analbuminemic rats Jaap A. Joles, D.V.M., Ph.D., Harry van Goor, Hein A. Koomans Kidney International Volume 53, Issue 4, Pages 862-868 (April 1998) DOI: 10.1111/j.1523-1755.1998.00825.x Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 1 Effects of estrogen on cholesterol (A) and triglycerides (B) in analbuminemic rats (NAR) after uninephrectomy (UNX). Symbols are: circles, ovariectomized females with estradiol (E2) implants (•) or without E2 (○); squares, ovariectomized females with E2 implants (▪) that were removed 12 weeks post-UNX (□); triangles, males with E2 implants (▴) or orchidectomized males without E2 (▵). *P < 0.01 versus ovariectomized or orchidectomized where applicable. Kidney International 1998 53, 862-868DOI: (10.1111/j.1523-1755.1998.00825.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 2 Effects of estrogen on proteinuria in analbuminemic rats (NAR) after uninephrectomy (UNX). Symbols are: circles, ovariectomized females with estradiol (E2) implants (•) or without E2 (○); squares, ovariectomized females with E2 implants (▪) that were removed 12 weeks post-UNX (□); triangles, males with E2 implants (▴) or orchidectomized males without E2 (▵). Note that proteinuria is indicated by a log scale. *P < 0.05 and **P < 0.01 versus ovariectomized or orchidectomized where applicable. Kidney International 1998 53, 862-868DOI: (10.1111/j.1523-1755.1998.00825.x) Copyright © 1998 International Society of Nephrology Terms and Conditions