Cardiac cycle DR S.PARTHASARATHY MD., DA., DNB., DIP. DIAB. PhD, FICA, IDRA, Diploma in software based statistics.

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Presentation transcript:

Cardiac cycle DR S.PARTHASARATHY MD., DA., DNB., DIP. DIAB. PhD, FICA, IDRA, Diploma in software based statistics

excitation of the myocardium Pressure gradient Contraction Opening of valves Ejection of blood Relax opening of valves Filling of blood

Pressure in Y axis and volume in X axis PV LOOP !! Pressure in Y axis and volume in X axis

Four important phases ventricular filling (phase a; diastole), isovolumetric contraction (phase b; systole), ejection (phase c; systole), and isovolumetric relaxation (phase d; diastole

end-diastolic pressure and end-diastolic volume (EDV) for the ventricle. As the ventricle begins to contract isovolumetrically (phase b), the mitral valve closes and the LVP increases, but the LV volume remains the same, resulting in a vertical line (all valves are closed).

Next !! Once LVP exceeds aortic diastolic pressure, the aortic valve opens (point 2) and ejection (phase c) begins. During this phase the LV volume decreases as LVP increases to a peak value (peak systolic pressure) and then decreases as the ventricle begins to relax.

Once LVP exceeds aortic diastolic pressure, the aortic valve opens (point 2) and ejection (phase c) begins. During this phase the LV volume decreases as LVP increases to a peak value (peak systolic pressure) and then decreases as the ventricle begins to relax

Next When the aortic valve closes (point 3), ejection ceases and the ventricle relaxes isovolumetrically - that is, the LVP falls but the LV volume remains unchanged, therefore the line is vertical (all valves are closed)

Next When the LVP falls below left atrial pressure, the mitral valve opens (point 4) and the ventricle begins to fill. Initially, the LVP continues to fall as the ventricle fills because the ventricle is still relaxing.

EF = stroke volume / EDV - 80/120 = 66 % Stroke volume = end diastolic volume – end systolic volume (80 = 120 -40) EF = stroke volume / EDV - 80/120 = 66 %

Refresh again !!

Diastolic dysfunction Becomes less compliant May be LVH slope of the EDPVR is the reciprocal of ventricular compliance

Exercise

Why do we want this class ??

Thank you all