Percentage of Hepatitis C Virus-Infected Hepatocytes Is a Better Predictor of Response Than Serum Viremia Levels Elena Rodríguez-Iñigo, Juan Manuel López-Alcorocho,

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Percentage of Hepatitis C Virus-Infected Hepatocytes Is a Better Predictor of Response Than Serum Viremia Levels Elena Rodríguez-Iñigo, Juan Manuel López-Alcorocho, Javier Bartolomé, Nuria Ortiz-Movilla, Margarita Pardo, Vicente Carreño The Journal of Molecular Diagnostics Volume 7, Issue 4, Pages 535-543 (October 2005) DOI: 10.1016/S1525-1578(10)60585-5 Copyright © 2005 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions

Figure 1 Box-plot representations of the percentage of infected hepatocytes and the serum HCV-RNA levels in responder and nonresponder patients. Each box is drawn from the lower quartile (Q1) to the upper quartile (Q3) and the horizontal lines across the boxes indicate the median. The whiskers are drawn from the Q3 to the maximum and from the Q1 to the minimum. Outliers are represented by empty dots. The Journal of Molecular Diagnostics 2005 7, 535-543DOI: (10.1016/S1525-1578(10)60585-5) Copyright © 2005 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions

Figure 2 ROC curve constructed with the probability values predicted with the logistic regression model, using no response as the state variable. AUC = 0.819; 95% confidence interval of AUC, 0.733–0.906. The Journal of Molecular Diagnostics 2005 7, 535-543DOI: (10.1016/S1525-1578(10)60585-5) Copyright © 2005 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions