Fig. 7. Altering GUCD1 expression reversed the effect of miR-370 on cell EMT process in HCC. (A) Western blot and (B) qRT-PCR results showed that GUCD1overexpression.

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Fig. 7. Altering GUCD1 expression reversed the effect of miR-370 on cell EMT process in HCC. (A) Western blot and (B) qRT-PCR results showed that GUCD1overexpression in miR-370-overexpressed HCCLM3 cells decreased E-cadherin expression and increased N-cadherin and Vimentin expression. (C)Western blot and (D) qRT-PCR results showed that GUCD1 knockdown in miR-370-suppressed Hep3B cells upregulated E-cadherin and downregulated N-cadherin and Vimentin significantly. *p<0.05. GUCD1, guanylylcyclase domain containing 1; EMT, epithelial-mesenchymal transition; HCC, hepatocellular carcinoma. Fig. 7. Altering GUCD1 expression reversed the effect of miR-370 on cell EMT process in HCC. (A) Western blot and (B) qRT- PCR results showed that GUCD1overexpression in miR-370-overexpressed HCCLM3 cells decreased E-cadherin expression and increased N-cadherin and Vimentin… Yonsei Med J. 2019 Mar;60(3):267-276. https://doi.org/10.3349/ymj.2019.60.3.267