Volume 388, Issue 10047, Pages (August 2016)

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Volume 388, Issue 10047, Pages 871-880 (August 2016) Cost and Outcome of Behavioural Activation versus Cognitive Behavioural Therapy for Depression (COBRA): a randomised, controlled, non-inferiority trial Prof David A Richards, PhD, David Ekers, PhD, Dean McMillan, PhD, Prof Rod S Taylor, PhD, Prof Sarah Byford, PhD, Fiona C Warren, PhD, Barbara Barrett, PhD, Paul A Farrand, PhD, Prof Simon Gilbody, DPhil, Prof Willem Kuyken, PhD, Heather O'Mahen, PhD, Prof Ed R Watkins, PhD, Kim A Wright, PhD, Prof Steven D Hollon, PhD, Nigel Reed, BSc, Shelley Rhodes, PhD, Emily Fletcher, MSc, Katie Finning, BSc The Lancet Volume 388, Issue 10047, Pages 871-880 (August 2016) DOI: 10.1016/S0140-6736(16)31140-0 Copyright © 2016 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions

Figure 1 Trial profile (A) 6 month, (B) 12 month, and (C) 18 month follow-up. BA=behavioural activation. CBT=cognitive behavioural therapy. *Includes four participants who were initially allocated in error and subsequently excluded. The Lancet 2016 388, 871-880DOI: (10.1016/S0140-6736(16)31140-0) Copyright © 2016 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions

Figure 2 Bootstrapped mean differences in costs and effects of BA compared with CBT BA=behavioural activation. CBT=cognitive behavioural therapy. NE=northeast. NW=northwest. SE=southeast. SW=southwest. QALY=quality-adjusted life-year. The Lancet 2016 388, 871-880DOI: (10.1016/S0140-6736(16)31140-0) Copyright © 2016 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions