Volume 11, Issue 2, Pages (October 2004)

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Volume 11, Issue 2, Pages 113-120 (October 2004) Atherogenesis and vascular calcification in mice expressing the human LPA gene Päivi A. Teivainen, Knut A. Eliassen, Kåre Berg, Kari Torsdalen, Aud Svindland Pathophysiology Volume 11, Issue 2, Pages 113-120 (October 2004) DOI: 10.1016/j.pathophys.2004.06.007 Copyright © 2004 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 Photomicrograph showing two aortic lesions in aortic root near cusps in female LPA-YAC/hAPOB transgenic mouse fed on the HC diet for 7 weeks. Figure shows a section with two separate plaques of fatty streak type (original magnification 100×). These plaques are presented with original magnification 400× in cuts (A) and (B). In cut (A) a lesion with accumulation of extracellular lipids and a single foam cell (arrow) on the endothelial surface is seen. In cut (B) a aortic lesion with calcification (arrows) is seen. Pathophysiology 2004 11, 113-120DOI: (10.1016/j.pathophys.2004.06.007) Copyright © 2004 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 Normalized hepatic apo(a) mRNA levels in female LPA-YAC and LPA-YAC/hAPOB transgenic mice fed three different diets for 7 weeks. HC: high-cholesterol diet, HCHF: high-cholesterol/high-fat diet. Pathophysiology 2004 11, 113-120DOI: (10.1016/j.pathophys.2004.06.007) Copyright © 2004 Elsevier Ireland Ltd Terms and Conditions