Six years' experience in ovum donation using vitrified oocytes: report of cumulative outcomes, impact of storage time, and development of a predictive.

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Presentation transcript:

Six years' experience in ovum donation using vitrified oocytes: report of cumulative outcomes, impact of storage time, and development of a predictive model for oocyte survival rate Ana Cobo, Ph.D., Nicolás Garrido, Ph.D., M.Sc., Antonio Pellicer, M.D., José Remohí, M.D. Fertility and Sterility Volume 104, Issue 6, Pages 1426-1434.e8 (December 2015) DOI: 10.1016/j.fertnstert.2015.08.020 Copyright © 2015 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 1 Distribution of the study population. Fertility and Sterility 2015 104, 1426-1434.e8DOI: (10.1016/j.fertnstert.2015.08.020) Copyright © 2015 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 2 The Kaplan–Meier plotting for the CDR depending on the total number of ETs until the first delivery is achieved from a single donation of vitrified oocytes. The panel shows the CDR with the 95% CI according to each transfer number. Fertility and Sterility 2015 104, 1426-1434.e8DOI: (10.1016/j.fertnstert.2015.08.020) Copyright © 2015 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 3 The Kaplan–Meier curve for the CDR of at least one baby, depending on the total number of oocytes consumed. Fertility and Sterility 2015 104, 1426-1434.e8DOI: (10.1016/j.fertnstert.2015.08.020) Copyright © 2015 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 4 The Kaplan–Meier curve for the CDR of at least one baby, depending on the total number of oocytes consumed, categorized by age (A); etiology = indication for ovum donation (B); and semen parameters (C). Overall comparisons: (A) Log-rank (Mantel-Cox), P=.027; Breslow (generalized Wilcoxon), P=.072; Tarone–Ware, P=.048. (B) Log-rank (Mantel-Cox), P=.325; Breslow (generalized Wilcoxon), P=.754; Tarone-Ware, P=.595. (C) Log-rank (Mantel-Cox), P=.813; Breslow (generalized Wilcoxon), P=.615; Tarone–Ware, P=.722. Fertility and Sterility 2015 104, 1426-1434.e8DOI: (10.1016/j.fertnstert.2015.08.020) Copyright © 2015 American Society for Reproductive Medicine Terms and Conditions