Transcription Initiation at Its Most Basic Level

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Transcription Initiation at Its Most Basic Level Ronen Marmorstein Cell Volume 115, Issue 4, Pages 370-372 (November 2003) DOI: 10.1016/S0092-8674(03)00888-2

Figure 1 Structure of the Initiator Binding Protein from T. vaginalis Upper left: structure of the IBP Inr binding domain, highlighting the helix-turn-helix (purple) motif embedded in the ETS-like domain and the unique 310 helix (orange) used for DNA recognition. Upper right: structure of the IBP-C domain bound to a C-terminal stand (red) from a crystallographically related IBP C domain that is proposed to mimic the CTD of RNA polymerase II. Lower panel: model of a IBP/Inr/RNA pol II complex with putative loops connecting the N and C domains of IBP and the CTD to the rest of RNA pol II, depicted as aqua and broken red loops, respectively. Cell 2003 115, 370-372DOI: (10.1016/S0092-8674(03)00888-2)