Time-lapse deselection model for human day 3 in vitro fertilization embryos: the combination of qualitative and quantitative measures of embryo growth 

Slides:



Advertisements
Similar presentations
Mouse strain and quality control testing: improved sensitivity of the mouse embryo assay with embryos from outbred mice Zaraq Khan, M.B.B.S., Heather S.
Advertisements

A time to look back: analysis of morphokinetic characteristics of human embryo development  Javier Herrero, Ph.D., Alberto Tejera, Ph.D., Carmela Albert,
Susannah Baruch, J.D., David Kaufman, Ph.D., Kathy L. Hudson, Ph.D. 
Human blastocyst morphological quality is significantly improved in embryos classified as fast on day 3 (≥10 cells), bringing into question current embryological.
Demián Glujovsky, M.D., M.Sc., Cynthia Farquhar, M.D., M.P.H. 
What is a difficult transfer
Study of nucleation status in the second cell cycle of human embryo and its impact on implantation rate  Jesus Aguilar, Ph.D., Irene Rubio, Ph.D., Elkin.
A giant oocyte in a cohort of retrieved oocytes: does it have any effect on the in vitro fertilization cycle outcome?  Ronit Machtinger, M.D., Joseph.
Longitudinal changes in maternal serum concentrations of antimüllerian hormone in individual women during conception cycles and early pregnancy  Kristina.
Susannah Baruch, J.D., David Kaufman, Ph.D., Kathy L. Hudson, Ph.D. 
Edward G. Hughes, M.B., F.R.C.S.(C.), Deirdre DeJean, M.Sc. 
Fertility and Sterility  Volume 97, Issue 3, Pages (March 2012)
Thyroid antibodies and gestational diabetes mellitus: a meta-analysis
Composition of single-step media used for human embryo culture
Relationship between pre-embryo pronuclear morphology (zygote score) and standard day 2 or 3 embryo morphology with regard to assisted reproductive technique.
Morphological embryo assessment: reevaluation
Successful delivery after the transfer of embryos obtained from a cohort of incompletely in vivo matured oocytes at retrieval time  Patricia Fauque, M.D.,
Zhi-Yong Yang, M.D., Ri-Cheng Chian, Ph.D.  Fertility and Sterility 
Can an educational DVD improve the acceptability of elective single embryo transfer? A randomized controlled study  Nicole Hope, M.B., B.S., Hon., Luk.
Gilad Karavani, M. D. , Assaf Ben-Meir, M. D. , Yoel Shufaro, M. D
Inmaculada Molina, Ph. D. , Juan V. Martínez, M. S. , José F
The relative contribution of assisted reproductive technologies and ovulation induction to multiple births in the United States 5 years after the Society.
Live birth of twins derived from zona-free oocytes
Birth defects in children conceived by in vitro fertilization and intracytoplasmic sperm injection: a meta-analysis  Juan Wen, B.S., Jie Jiang, B.S.,
How old is too old? Challenges faced by clinicians concerning age cutoffs for patients undergoing in vitro fertilization  Robert L. Klitzman, M.D.  Fertility.
Predictive value of embryo grading for embryos with known outcomes
Randomized, controlled pilot trial of natural versus hormone replacement therapy cycles in frozen embryo replacement in vitro fertilization  Ginny Mounce,
Cited2 protein level in cumulus cells is a biomarker for human embryo quality and pregnancy outcome in one in vitro fertilization cycle  Yuan Fang, Ph.D.,
Juliette Koch, M. R. A. N. Z. C. O. G. , Michael F. Costello, F. R. A
Martin D. Keltz, M. D. , Josh C. Skorupski, M. D. , Katrina Bradley, M
Hysteroscopic local anesthetic intrauterine cornual block in office endometrial ablation: a randomized controlled trial  Vinod Kumar, Ph.D., Konstantinos.
Automatic time-lapse instrument is superior to single-point morphology observation for selecting viable embryos: retrospective study in oocyte donation 
Composition of commercial media used for human embryo culture
Influence of acupuncture stimulation on pregnancy rates for women undergoing embryo transfer  Caroline Smith, Ph.D., Meaghan Coyle, B.Hlth.Sc. (Acup.),
Daniel Bodri, M. D. , M. Sc. , Ph. D. , Takeshi Sugimoto, M. Sc
A comparison of three downregulation approaches for poor responders undergoing in vitro fertilization  Laura Detti, M.D., Daniel B. Williams, M.D., Jared.
Embryo multinucleation at the two-cell stage is an independent predictor of intracytoplasmic sperm injection outcomes  Laurent Desch, M.D., Céline Bruno,
Morphokinetic analysis and embryonic prediction for blastocyst formation through an integrated time-lapse system  Yamileth Motato, Ph.D., María José de.
Using the Society for Assisted Reproductive Technology Clinic Outcome System morphological measures to predict live birth after assisted reproductive.
Normal birth after single-embryo transfer in a patient with excessive polypronuclear zygote formation following in vitro fertilization and intracytoplasmic.
Impact of oocyte donation on perinatal outcome in twin pregnancies
Venous thromboembolism in relation to in vitro fertilization: an approach to determining the incidence and increase in risk in successful cycles  Karin.
Should embryos developing to blastocysts on day 7 be cryopreserved and transferred: an analysis of pregnancy and implantation rates  George Kovalevsky,
Age-specific probability of live birth with oocyte cryopreservation: an individual patient data meta-analysis  Aylin Pelin Cil, M.D., Heejung Bang, Ph.D.,
Ongoing twin pregnancy after rescue intracytoplasmic sperm injection of unfertilized abnormal oocytes  Navid Esfandiari, D.V.M., Ph.D., H.C.L.D., E. Anne.
Cumulative newborn rates increase with the total number of transferred embryos according to an analysis of 15,792 ovum donation cycles  Nicolás Garrido,
The forgotten coil Fertility and Sterility
Kirstine Kirkegaard, M. D. , Johnny Juhl Hindkjaer, M. Sc
Ri-Cheng Chian, Ph.D., Peter S. Uzelac, M.D., Geeta Nargund, M.D. 
Tong Du, M. S. , Hong Chen, M. D. , Rong Fu, M. S. , Qiuju Chen, Ph. D
Examining the efficacy of six published time-lapse imaging embryo selection algorithms to predict implantation to demonstrate the need for the development.
José Bellver, M. D. , Yanira Ayllón, M. D. , Marcos Ferrando, M. D
Website quality assessment: Mistaking apples for oranges
Effects of early cleavage patterns of human embryos on subsequent in vitro development and implantation  Yamato Mizobe, M.S., Naoto Oya, M.S., Reiko Iwakiri,
Failed IVF cycles and the risk of subsequent preeclampsia or fetal growth restriction: a case-control exploratory study  Ioanna Tsoumpou, M.D., Ahmed.
In Vitro Fertilization (IVF) Intracytoplasmic Sperm Injection (ICSI) Using Sperm Exposed to Cyclophosphamide Reduces Preimplantation Embryo Development.
Impact of subclinical hypothyroidism in women with recurrent early pregnancy loss  Lia A. Bernardi, M.D., Ronald N. Cohen, M.D., Mary D. Stephenson, M.D.,
Current evaluation of amenorrhea
Genetic evaluation procedures at sperm banks in the United States
Assessing the reproductive competence of individual embryos: a proposal for the validation of new “-omics” technologies  Richard T. Scott, M.D., H.C.L.D.,
David H. Barad, M.D., M.S., Norbert Gleicher, M.D. 
In vitro sildenafil citrate use as a sperm motility stimulant
Are urinary bisphenol A levels in men related to semen quality and embryo development after medically assisted reproduction?  Jure Knez, M.D., Roman Kranvogl,
Influence of different oocyte insemination techniques on early and late morphokinetic parameters: retrospective analysis of 500 time-lapse monitored blastocysts 
Randomized, controlled pilot trial of natural versus hormone replacement therapy cycles in frozen embryo replacement in vitro fertilization  Ginny Mounce,
Comparisons of inhibin B versus antimüllerian hormone in poor ovarian responders undergoing in vitro fertilization  Rongrong Tan, M.M.Sc., Danhua Pu,
A time to look back: analysis of morphokinetic characteristics of human embryo development  Javier Herrero, Ph.D., Alberto Tejera, Ph.D., Carmela Albert,
Oocyte retrieval timing based on spontaneous luteinizing hormone surge during natural cycle in vitro fertilization treatment  Daniel Bodri, M.D., M.Sc.,
In vitro development and chromosome constitution of embryos derived from monopronucleated zygotes after intracytoplasmic sperm injection  Sílvia Mateo,
Maternal serum screening markers and nuchal translucency measurements in in vitro fertilization pregnancies: a systematic review  Andrea Lanes, M.Sc.,
Presentation transcript:

Time-lapse deselection model for human day 3 in vitro fertilization embryos: the combination of qualitative and quantitative measures of embryo growth  Yanhe Liu, M.Sc., Vincent Chapple, M.B., B.S., Katie Feenan, M.Sc., Peter Roberts, Ph.D., Phillip Matson, Ph.D.  Fertility and Sterility  Volume 105, Issue 3, Pages 656-662.e1 (March 2016) DOI: 10.1016/j.fertnstert.2015.11.003 Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Flow chart for embryo classification using both qualitative and quantitative parameters to assess implantation potential. Fertility and Sterility 2016 105, 656-662.e1DOI: (10.1016/j.fertnstert.2015.11.003) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Implantation rates of KID embryos (n = 270) fertilized via IVF (n = 105) or ICSI (n = 165) according to different grades assessed using the proposed model. Fertility and Sterility 2016 105, 656-662.e1DOI: (10.1016/j.fertnstert.2015.11.003) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 1 Comparison of frequency distribution in time to reach 5-cell stage relative to pronuclear fading (T5_PNF) between all (A, n = 270) and deselected (B, n = 166) embryos. Fertility and Sterility 2016 105, 656-662.e1DOI: (10.1016/j.fertnstert.2015.11.003) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions