Use of Recombinant Activated Factor VII Concentrate to Control Postoperative Hemorrhage in Complex Cardiovascular Surgery Lyndsey J. Bowman, Walter E.

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Presentation transcript:

Use of Recombinant Activated Factor VII Concentrate to Control Postoperative Hemorrhage in Complex Cardiovascular Surgery Lyndsey J. Bowman, Walter E. Uber, Pharm D, Martha R. Stroud, Lydia R. Christiansen, John Lazarchick, Arthur J. Crumbley, MD, John M. Kratz, MD, John M. Toole, MD, Fred A. Crawford, MD, John S. Ikonomidis, MD, PhD The Annals of Thoracic Surgery Volume 85, Issue 5, Pages 1669-1677 (May 2008) DOI: 10.1016/j.athoracsur.2008.01.089 Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Transfusion requirements before (solid bars) recombinant activated factor VII administration and after (open bars) administration (n = 36). (Cryo = cryoprecipitate; FFP = fresh frozen plasma; RBC = red blood cells.) The Annals of Thoracic Surgery 2008 85, 1669-1677DOI: (10.1016/j.athoracsur.2008.01.089) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Chest tube output before (solid bars) recombinant activated factor VII (rFVIIa) administration (output averaged over 4 hours before receiving rFVIIa in the intensive care unit [ICU]) and after (open bars) administration (output averaged over 4 hours after receiving rFVIIa in the ICU). The Annals of Thoracic Surgery 2008 85, 1669-1677DOI: (10.1016/j.athoracsur.2008.01.089) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions