Influences on endometrial development during intrauterine insemination: clinical experience of 2,929 patients with unexplained infertility Erin Foran.

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Presentation transcript:

Influences on endometrial development during intrauterine insemination: clinical experience of 2,929 patients with unexplained infertility Erin Foran Wolff, M.D., Nima Vahidi, Connie Alford, M.D., Kevin Richter, Ph.D., Eric Widra, M.D. Fertility and Sterility Volume 100, Issue 1, Pages 194-199.e1 (July 2013) DOI: 10.1016/j.fertnstert.2013.03.023 Copyright © 2013 Terms and Conditions

Figure 1 (A) Scatter plot illustrating serum E2 concentration at trigger according to patient age, including linear regression trend line. (B) Illustration of trends in serum E2 concentration and endometrial thickness according to body mass index (BMI) categorization (<20 = underweight; 20–24 = normal weight; 25–29 = overweight; 30–34 = obese; >35 = very obese), with linear regression models indicated. (C) Scatter plot illustrating endometrial thickness at trigger according to patient age, including linear regression trend line. (D) Scatter plot illustrating endometrial thickness at trigger according to serum E2 concentration, including linear regression trend line. Fertility and Sterility 2013 100, 194-199.e1DOI: (10.1016/j.fertnstert.2013.03.023) Copyright © 2013 Terms and Conditions

Figure 2 Diagram of patterns of association among age, body mass index (BMI), mature follicles, serum E2, and endometrial thickness. Arrows indicate statistically significant associations between independent and dependent variables. Partial regression coefficients were derived from multiple regression models and indicate estimated unit changes in dependent variables per unit change in independent variables. Fertility and Sterility 2013 100, 194-199.e1DOI: (10.1016/j.fertnstert.2013.03.023) Copyright © 2013 Terms and Conditions

Figure 3 Illustration of clinical pregnancy rates (PR) according to endometrial thickness at trigger, with sample sizes indicated. Fertility and Sterility 2013 100, 194-199.e1DOI: (10.1016/j.fertnstert.2013.03.023) Copyright © 2013 Terms and Conditions

Supplemental Figure 1 Multiple pregnancy rates (PR) per clinical pregnancy according to the number of mature follicles (≥14 mm) at trigger, with sample sizes indicated. Triplets are shown in red and twins in blue. Fertility and Sterility 2013 100, 194-199.e1DOI: (10.1016/j.fertnstert.2013.03.023) Copyright © 2013 Terms and Conditions