The Predecessors Within

Slides:

Advertisements

Similar presentations

SOD1 Integrates Signals from Oxygen and Glucose to Repress Respiration Amit R. Reddi, Valeria C. Culotta Cell Volume 152, Issue 1, Pages (January.

Advertisements

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.

The RAG Recombinase Dictates Functional Heterogeneity and Cellular Fitness in Natural Killer Cells Jenny M. Karo, David G. Schatz, Joseph C. Sun Cell Volume.

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell

Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity Michael S. Rooney, Sachet A. Shukla, Catherine J. Wu, Gad Getz,

Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni

Common Sense about Taste: From Mammals to Insects David A. Yarmolinsky, Charles S. Zuker, Nicholas J.P. Ryba Cell Volume 139, Issue 2, Pages (October.

UvrD Helicase Unwinds DNA One Base Pair at a Time by a Two-Part Power Stroke Jae Young Lee, Wei Yang Cell Volume 127, Issue 7, Pages (December.

Nucleation and Transport Organize Microtubules in Metaphase Spindles Jan Brugués, Valeria Nuzzo, Eric Mazur, Daniel J. Needleman Cell Volume 149, Issue.

Eph-Ephrin Bidirectional Signaling in Physiology and Disease Elena B. Pasquale Cell Volume 133, Issue 1, Pages (April 2008) DOI: /j.cell

The Monarch Butterfly Genome Yields Insights into Long-Distance Migration Shuai Zhan, Christine Merlin, Jeffrey L. Boore, Steven M. Reppert Cell Volume.

Evolution of the Cancer Stem Cell Model Antonija Kreso, John E. Dick Cell Stem Cell Volume 14, Issue 3, Pages (March 2014) DOI: /j.stem

Nuclear Receptors, RXR, and the Big Bang Ronald M. Evans, David J. Mangelsdorf Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell

The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer Genomes Tae-Min Kim, Peter W. Laird, Peter J. Park Cell Volume 155, Issue.

Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.

The Good Fat Cell Volume 147, Issue 7, (December 2011) DOI: /j.cell Copyright © 2011 Terms and Conditions Terms and Conditions.

Genomewide Comparison of DNA Sequences between Humans and Chimpanzees Ingo Ebersberger, Dirk Metzler, Carsten Schwarz, Svante Pääbo The American Journal.

Mutually Exclusive Binding of Telomerase RNA and DNA by Ku Alters Telomerase Recruitment Model Jennifer S. Pfingsten, Karen J. Goodrich, Cornelius Taabazuing,

Gastrulation Movements: the Logic and the Nuts and Bolts Maria Leptin Developmental Cell Volume 8, Issue 3, Pages (March 2005) DOI: /j.devcel

Sex-Specific Aging in Flies, Worms, and Missing Great-Granddads

The KEOPS Complex: A Rosetta Stone for Telomere Regulation?

DNA Phenotyping: Snapshot of a Criminal

TLRs of Our Fathers Immunity

MDS Is a Stem Cell Disorder After All

Mapping Human Epigenomes

Autophagy: Paying Charon's Toll

Introgression of Neandertal- and Denisovan-like Haplotypes Contributes to Adaptive Variation in Human Toll-like Receptors Michael Dannemann, Aida M.

Pioneering a Global Cure for Chronic Hepatitis C Virus Infection

Not All DDRs Are Created Equal: Non-Canonical DNA Damage Responses

Retrotransposition and Structural Variation in the Human Genome

Lock and Key to Transcription: σ-DNA Interaction

Human Evolutionary Genomics

In This Issue Cell Volume 158, Issue 5, (August 2014)

Volume 26, Issue 24, Pages (December 2016)

Putting the Balance Back in Diet

Gene Discovery for Complex Traits: Lessons from Africa

Eukaryotic Transcription Activation: Right on Target

The Platypus Genome Unraveled

A New Way to Diversify Antibodies by DNA Transposition

Volume 152, Issue 1, (January 2013)

The Human Condition—A Molecular Approach

Volume 173, Issue 1, Pages e9 (March 2018)

The Ribosome Emerges from a Black Box

Volume 49, Issue 2, Pages (January 2013)

Volume 130, Issue 6, (September 2007)

A Molecular Take on Aesop’s The Oak and the Reeds

Genome Sequences from Extinct Relatives

Volume 143, Issue 6, (December 2010)

Selina Vattathil, Joshua M. Akey Cell

Forging New Ties between E. coli Genes

A Movie of RNA Polymerase II Transcription

The Cell Biology of Genomes: Bringing the Double Helix to Life

Both Layers of the COPII Coat Come into View

Death in the CNS: Six-Microns-Under

The Plasticity of Aging: Insights from Long-Lived Mutants

The KEOPS Complex: A Rosetta Stone for Telomere Regulation?

Learning from the Uncontrollable

Neanderthal and Denisovan retroviruses in modern humans

Complex History of Admixture between Modern Humans and Neandertals

Paleogenomics of Archaic Hominins

Volume 163, Issue 4, (November 2015)

Volume 163, Issue 2, (October 2015)

TLRs of Our Fathers Immunity

Microbial Skin Inhabitants: Friends Forever

Introgression of Neandertal- and Denisovan-like Haplotypes Contributes to Adaptive Variation in Human Toll-like Receptors Michael Dannemann, Aida M.

Volume 134, Issue 6, (September 2008)

Human Evolution: Genomic Gifts from Archaic Hominins

In This Issue Cell Volume 145, Issue 3, (April 2011)

Genomics in Africa: Avoiding Past Pitfalls

Volume 148, Issue 1, (January 2012)

Presentation transcript:

The Predecessors Within . . . Benjamin Vernot, Svante Pääbo Cell Volume 173, Issue 1, Pages 6-7 (March 2018) DOI: 10.1016/j.cell.2018.03.023 Copyright © 2018 Elsevier Inc. Terms and Conditions

Figure 1 Interactions between Archaic Hominins and Modern Humans Top: Relationships between archaic hominins and modern humans. Arrows show the minimum number of interbreedings between Denisovan, Neanderthal, and modern human populations necessary to produce the results in Browning et al. The dark blue arrow from Denisovans to East Asians is newly presented in this work. We note that additional genetic interactions between and among archaics and modern humans are possible, and even likely, and that much of the timing and details of the illustrated interactions are still unknown. Bottom: Map showing locations of Neanderthal and Denisovan bones with sequenced genomes (green dots, Neanderthals; blue dot, Denisovan) and rough ranges of DNA contributions from these groups in humans today (Sankararaman et al., 2016). Cell 2018 173, 6-7DOI: (10.1016/j.cell.2018.03.023) Copyright © 2018 Elsevier Inc. Terms and Conditions